About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Stem Cells to Curb Appetite

by Sheela Philomena on April 6, 2013 at 11:09 AM
Font : A-A+

 Stem Cells to Curb Appetite

A recent discovery made by researchers in stem cell manipulation could offer solution to obesity.

It was previously thought that the nerve cells in the brain associated with appetite regulation were generated entirely during an embryo's development in the womb and therefore their numbers were fixed for life.

Advertisement

But a new study has identified a population of stem cells capable of generating new appetite-regulating neurons in the brains of young and adult rodents.

Obesity has reached epidemic proportions globally. More than 1.4 billion adults worldwide are overweight and more than half a billion are obese.
Advertisement

Associated health problems include type 2 diabetes, heart disease, arthritis and cancer, and at least 2.8 million people die each year as a result of being overweight or obese.

The economic burden on the NHS in the UK is estimated to be more than 5 billion pounds annually. In the US, the healthcare cost tops 60 billion dollars.

Scientists at UEA investigated the hypothalamus section of the brain - which regulates sleep and wake cycles, energy expenditure, appetite, thirst, hormone release and many other critical biological functions.

The study looked specifically at the nerve cells that regulate appetite.

The researchers used "genetic fate mapping" techniques to make their discovery - a method that tracks the development of stem cells and cells derived from them, at desired time points during the life of an animal.

They established that a population of brain cells called "tanycytes" behave like stem cells and add new neurons to the appetite-regulating circuitry of the mouse brain after birth and into adulthood.

Lead researcher Dr Mohammad K. Hajihosseini, from UEA's school of Biological Sciences said, "Unlike dieting, translation of this discovery could eventually offer a permanent solution for tackling obesity."

"Loss or malfunctioning of neurons in the hypothalamus is the prime cause of eating disorders such as obesity," he said.

He said that this study has shown that the neural circuitry that controls appetite is not fixed in number and could possibly be manipulated numerically to tackle eating disorders.

The research is published in the Journal of Neuroscience.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
Long-Term Glycemic Control - A Better Measure of COVID-19 Severity
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Diet Pills Stem Cells - Cord Blood Stem Cells - Fundamentals Parkinsons Disease Surgical Treatment Genetics and Stem Cells Bone Marrow Transplantation Tissue Engineering and Regenerative Medicine Stem Cells Increased Appetite Symptom Evaluation Hungry? - But you Just Ate! 

Recommended Reading
Obesity
Obesity is a condition where there is excess accumulation of body fat which poses a risk to the ......
Quiz on Stem Cells
Scientists believe (and are working hard) to use stem cells in the future to treat a wide range of ....
Body Mass Index
The BMI calculator helps you assess your weight indicating if it is normal or if you are ......
How to Lose Weight?
Slide show which explains obesity causes and tips on how to lose weight. Exercising before ......
Bone Marrow Transplantation
Preferred Term is Hematopoietic stem cell transplantation. In this stem cell from bone marrow are in...
Diet Pills
Diet pills are flooding the market by millions. The positive side of diet pills to most people is th...
Hungry? - But you Just Ate!
Most of us are tempted by good food, mealtime or not. Once in a way is fine but it is dangerous to g...
Increased Appetite Symptom Evaluation
An increase in appetite is seen in conditions like bulimia, diabetes, hyperthyroidism and worm ......
Stem Cells - Fundamentals
Encyclopedia section of medindia gives general info about Stem Cells...
Stem Cells - Cord Blood
Encyclopedia section of medindia gives general info about Cord Blood...
Tissue Engineering and Regenerative Medicine
This new field is an amalgamation of biology, medicine and engineering, and is believed to have mind...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use