Medindia
Advertisement

Scientists Identify New Drug to Treat Lung Cancer

by Bidita Debnath on January 27, 2015 at 11:33 PM

 Scientists Identify New Drug to Treat Lung Cancer
Researchers have identified a potential new drug target for treating lung cancer.

In a new study by University of Kentucky Markey Cancer Center researchers have suggested that targeting a key enzyme and its associated metabolic programming may lead to novel drug development to treat the disease.
Advertisement

The study collected metabolic data directly from more than 120 human lung cancer patients. UK's Center for Environmental and Systems Biochemistry (CESB) researchers measured the in situ activity of the two enzymes in patients with early stage lung cancer. When they infused the patients with a glucose tagged with stable heavy atoms immediately prior to surgical removal of tumor tissue, they found that PC was selectively activated - in other words, PC expression may play an important role in the development of lung cancer.

Teresa Fan, one of the lead researchers of the study, said that they now knew much more about metabolic reprogramming of cancerous tissues in human patients, particularly that the activation of pyruvate carboxylase is important to lung cancer cell growth and survival. Ultimately, figuring out how to target PC may help researchers develop new, more effective therapeutic strategies to improve upon current lung cancer treatments, which are limited and harmful.

The study is published in the Journal of Clinical Investigation.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Lower Respiratory Tract Infections Linked to Obstructive Sleep Apnea in Children
Type 2 Diabetes can be Controlled by Unripen Green Jackfruit Flour
Covid Pandemic: How Parents can Help Kids Deal with Back-to-School Anxiety
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drug Toxicity Lung Biopsy Lung Cancer Cancer and Homeopathy Clinical Trials - Different Phases of the trial Signature Drug Toxicity Cancer Facts Asbestosis Cancer Tattoos A Body Art 

Recommended Reading
Risk of Lung Cancer Less in People Living at Higher Altitudes
Risk of lung cancer is much less in people living at higher altitudes, in both smokers and ......
Collaboration Will Help Improve Lung Cancer Surgery Outcomes
Collaboration between The Society of Thoracic Surgeons and European Society of Thoracic Surgery ......
Instability of TIAM1 Protein Spreads Lung Cancer
Recent research has spotted the reasons for the spread of lung cancer which could be a boon in ......
Spread of Lung Cancer Revealed
The mystery behind the spreading of lung cancer was revealed by scientists....
Asbestosis
Asbestosis is a chronic inflammatory lung disease that occurs due to long term exposure to asbestos ...
Clinical Trials - Different Phases of the trial
Clinical trials serve as a vital component for improving the treatment of medical conditions as they...
Drug Toxicity
Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a d...
Lung Biopsy
The procedure by which tissue samples are obtained from the lung is known as lung biopsy. The biopsy...
Lung Cancer
Lung cancer is a malignant tumor in the lung tissues. Smoking is the main cause of lung cancer with ...
Tattoos A Body Art
Tattoos are a rage among college students who sport it for the ‘cool dude’ or ‘cool babe’ look...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use