About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Scientists Discover Potential Asthma Treatment

by Sheela Philomena on May 21, 2014 at 4:54 PM
Font : A-A+

 Scientists Discover Potential Asthma Treatment

An antibody that can improve the quality of life for individuals with asthma by relieving inflammation in the lungs has been discovered by scientists.

The research was led by Dr. Gail Gauvreau, associate professor at McMaster University and Dr. Paul O'Byrne, executive director of the Firestone Institute of Respiratory Health (FIRH) at St. Joseph's Healthcare Hamilton and chair, Department of Medicine at McMaster University.

Advertisement

The study was presented at the American Thoracic Society conference in San Diego. It concluded that blocking a specific protein in the lungs with an antibody both alleviates baseline inflammation and provides resistance to allergens for those with mild allergic asthma.

"It was known that the epithelial cells which line the airways in the lungs produce a protein called thymic stromal lymphopoietin (TSLP) that causes inflammation. This study, for the first time, proved that these cells continually produce this protein in humans with asthma," O'Byrne said.
Advertisement

"While we studied patients with allergic asthma, this research opens the door for the development of new treatments not only for this population, but for those diagnosed with severe asthma as well," he said.

Individuals with allergic asthma are typically treated with inhaled corticosteroids or bronchodilators that help to control their asthma when taken regularly.

While antibodies are typically reserved for severe asthma, this research can lead to antibody treatment for those who have mild allergic asthma.

This study can lead to quality of life improvements for those with allergic asthma that have issues with inhalers or steroid-based medications.

The study - conducted by the Clinical Investigator Collaborative, a multi-centre, Phase II clinical trials group supported by the Allergy, Genes and Environment Network (AllerGen) - recruited 31 patients over five sites across Canada.

After 12 weeks of participant monitoring, the antibodies significantly reduced baseline inflammation and protected the participants against inhaled allergens when compared to a placebo.

The study is published in the New England Journal of Medicine.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
First Dose of COVID-19 Vaccines May Improve Mental Health
Printed Temperature Sensors help with Continuous Temperature Monitoring
Health Benefits of Giloy
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Childhood Asthma Asthma Remedies for Seasonal Allergy Relief Allergy - Symptom Evaluation Wheezing Churg-Strauss Syndrome Tests for Asthma Stay Well This Winter Occupational Asthma 

Recommended Reading
Asthma
It's a lung condition characterized by inflammation of the bronchi and constriction of the airways ....
Quiz on Asthma
Come winter and asthma is back with renewed vengeance. With air pollution ever on the rise and our ....
ASTHMA
Learn more about Asthma, a chronic childhood disease with the highest incidence. ...
Allergy - Symptom Evaluation
An allergic reaction may be mild or severe. It usually involves the skin, respiratory system, eyes,...
Childhood Asthma
Childhood asthma is a condition that affects airways in children and interferes with their daily act...
Churg-Strauss Syndrome
Churg-Strauss Syndrome is a rare disease characterized by inflammation of blood vessels that can res...
Occupational Asthma
Occupational Asthma (OA) is a lung disorder that occurs due to exposure to toxic substances at the w...
Remedies for Seasonal Allergy Relief
Understanding the cause and mechanism of seasonal allergy can help in choosing the right treatment. ...
Stay Well This Winter
Winter is associated with staying huddled indoors, people scurrying home to escape the piercing wint...
Tests for Asthma
Do you find it difficult to breathe especially during the cold weather? You may need to get tested f...
Wheezing
Wheezing is a sound arising from the airways due to an obstruction or narrowing, which prevents the ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use