About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Scientists Discover Parts of Brain Cells That Trigger Eating Disorders

by Sheela Philomena on September 27, 2013 at 4:12 PM
Font : A-A+

 Scientists Discover Parts of Brain Cells That Trigger Eating Disorders

Cellular components that are responsible for triggering eating disorders have been discovered by scientists.

The finding lends insight into a cause for obesity and could lead to treatments for anorexia, bulimia nervosa, and binge eating disorder.

Advertisement

Senior study author Garret Stuber, PhD, assistant professor in the department of psychiatry and department of cell biology and physiology, said that the study underscores that obesity and other eating disorders have a neurological basis.

Stuber focused on one cell type-gaba neurons in the bed nucleus of the stria terminalis, or BNST, which is an outcropping of the amygdala, the part of the brain associated with emotion.
Advertisement

The BNST also forms a bridge between the amygdala and the lateral hypothalamus, the brain region that drives primal functions like eating, sexual behaviour, and aggression.

The BNST gaba neurons have a cell body and a long strand with branched synapses that transmit electrical signals into the lateral hypothalamus.

Stuber and his team wanted to stimulate those synapses by using an optogenetic technique, an involved process that would let him stimulate BNST cells simply by shining light on their synapses.

Stuber's team used genetically engineered proteins - from algae - that are sensitive to light and used genetically engineered viruses to deliver them into the brains of mice. Those proteins then get expressed only in the BNST cells, including in the synapses that connect to the hypothalamus.

His team then implanted fiber optic cables in the brains of these specially-bred mice, and this allowed the researchers to shine light through the cables and onto BNST synapses.

As soon as the light hit BNST synapses the mice began to eat voraciously even though they had already been well fed. Moreover, the mice showed a strong preference for high-fat foods.

The study has been published in the journal Science.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Parkinsons Disease Parkinsons Disease Surgical Treatment Bulimia Nervosa Sleep Eating Disorders Brain Brain Facts Ataxia Language Areas in The Brain Ways to Improve your Intelligence Quotient (IQ) Eating Disorders 

Recommended Reading
Sleep Eating Disorders
Sleep-related eating disorders are abnormal eating behaviors that occur during night. Sleep related ...
Anorexia Nervosa
Anorexia nervosa is an eating disorder most commonly found among teenage girls. Anorexia nervosa is ...
Quiz on Anorexia / Bulimia
Anorexia Nervosa - is it a psychological disorder , or simply an eating disorder gotten out of ......
Binge Eating may be Linked to Suicidal Behavior
Young African American girls who binge eat are more likely to report suicide attempts, suggests ......
Ataxia
Ataxia affects coordination. Gait becomes unstable and the patient loses balance. The cerebellum or ...
Bulimia Nervosa
The term ''Bulimia'' refers to episodes of uncontrolled excessive eating, known as "binges," followe...
Eating Disorders
Eating disorders involve extreme attitudes and behaviors towards food and weight. It has the highest...
Language Areas in The Brain
The mechanism of how human brain processes the language to express and comprehend the verbal, writte...
Parkinsons Disease
Parkinson’s disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...
Ways to Improve your Intelligence Quotient (IQ)
Intelligence quotient (IQ) is a psychological measure of human intelligence. Regular physical and me...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use