About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Researchers Identify Protein That can be Targeted to Treat Alzheimer's at Early Stage

by Kathy Jones on December 1, 2013 at 8:12 PM
Font : A-A+

 Researchers Identify Protein That can be Targeted to Treat Alzheimer's at Early Stage

Early accumulation of a small protein, known as amyloid beta, in the blood vessels of the brain can drive early cognitive impairment, a team of researchers has discovered.

The findings by Stony Brook University researchers suggested that targeting early buildup of amyloid in brain blood vessels could be a potential treatment strategy in early stage disease.

Advertisement

When amyloid accumulates and aggregates in the Alzheimer's disease process, amyloid deposits as either structures known as amyloid plaques around neuronal cells or deposits of amyloid in the blood vessels of the brain.

The team, led by William Van Nostrand, compared two disease models - one that developed amyloid plaques and the other that developed cerebral blood vessel amyloid.
Advertisement

The team assessed cognitive abilities at intervals and found that at three months, the model with brain blood vessel amyloid were cognitively impaired but the model with amyloid plaques were not cognitively impaired.

"Our results are intriguing because it appears cerebrovascular amyloid rather than amyloid plaques around neuronal cells is an early influence on cognitive decline," Dr. Van Nostrand said. "This opens the door to continued investigation on the role of amyloid on brain blood vessels in the Alzheimer's disease process and could be a first step toward developing more effective treatment targets for the onset of amyloid-associated cognitive impairment based on this particular type of amyloid buildup and associated pathologies."

The study was published in the Journal of Alzheimer's Disease.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Breast Cancer Awareness Month 2021 - It's time to RISE
First-Ever Successful Pig-To-Human Kidney Transplantation
World Osteoporosis Day 2021 -
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Alzheimers Disease Magical Millets for Your Health Diet and Nutrition Tips for Athletes Nutrition IQ Diet and Alzheimer´s Disease Genetics of Alzheimer´s disease 

Recommended Reading
Alzheimers Disease
Alzheimer's disease is a progressive neurodegenerative disease affecting memory and thinking and ......
Brain Exercises to Improve Memory
An active brain can certainly help in improving memory by strengthening the connections between ......
Undetected Nutrient Deficiencies: The Cause of Ill Health
Micronutrient and antioxidant deficiencies are most common and go unnoticed. They are the root ......
Vitamin B12 - An Essential Vitamin
If you feel that the persistent or regular incidences of depression have got nothing to do with ......
Diet and Alzheimer´s Disease
Alzheimer''s begins with forgetfulness, but over time affects speech and coordination along with dra...
Diet and Nutrition Tips for Athletes
Athletes can be physically fit by consuming a well balanced nutritious diet, which keeps them mental...
Genetics of Alzheimer´s disease
There are numerous genes that have been discovered that are associated with Alzheimer’s disease and ...
Magical Millets for Your Health
Millets are far more nutrient dense than wheat and rice. They are inexpensive and tasty too. Nutriti...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use