Researchers have witnessed how an enzyme works at the atomic level to repair sun-damaged DNA in a recent study. The discovery may prove to be a stepping-stone in future sunburn remedies and skin cancer prevention. Dongping Zhong and his colleagues from Ohio State University describe how they were able to observe the enzyme, called photolyase, inject a single electron and proton into an injured strand of DNA. The two subatomic particles healed the damage in a few billionths of a second. "It sounds simple, but those two atomic particles actually initiated a very complex series of chemical reactions," Nature quoted Zhong as saying. "It all happened very fast, and the timing had to be just right. "People have been working on this for years, but now that we've seen it, I don't think anyone could have guessed exactly what was happening," said Zhong. Zhong and colleagues synthesized DNA in the lab and exposed it to ultraviolet light, producing damage similar to that of sunburn, then added photolyase enzymes. Using ultrafast light pulses, they took a series of "snapshots" to reveal how the enzyme repaired the DNA at the atomic level. The study has revealed that photolyase breaks up those errant bonds in just the right spots to cause the atoms in the DNA to move back into their original positions. The bonds are then arranged in such a way that the electron and proton are automatically ejected out of the DNA helix and back into the photolyase, presumably so it could start the cycle over again and go on to heal other sites. Now that researchers know the mechanism by which photolyase works, they might use that information to design drugs or lotions that heal sun damage, Zhong said. The findings were published in the online edition of the journal Nature.Source: ANI << 300 Persons in Midnapore Affected by Food Poisoning Air Pollution in Traffic Leads to Sudden Cardiac Death >> Recommended Reading Skin Biopsy Encyclopedia section of medindia gives general information about skin biopsy. READ MORE Skin Disease Skin diseases also known as dermatologic disorders are many in number and so are their causes. The common skin diseases or skin disorders are usually related to the epidermal layer of skin. READ MORE DNA Finger Printing DNA fingerprinting is a technique which helps forensic scientists and legal experts solve crimes, identity thefts, legal suits and terrorism cases. READ MORE Epigenetics In the recent years ‘epigenetics’ represents inheritable changes in gene expression that do not include DNA alterations. READ MORE Food Preservatives - How Safe Are They? Food preservatives are basically antimicrobials or anti-oxidants that help preserve food by destroying the microbes and stopping decomposition of food products. READ MORE Most Popular on Medindia Blood - Sugar Chart Sanatogen Blood Donation - Recipients More News on: DNA Finger PrintingEpigeneticsFood Preservatives - How Safe Are They?