Research indicates that major changes occur in the brain during sleep to flush out waste and ward off disease.
The research in the journal Science offers new answers to explain why people spend a third of their lives asleep and may help in treating dementia and other neurological disorders.
Ageing and Sleep
Sleep is a barometer of good health in the elderly. Sleep problems in the elderly are controlled by various external and internal factors.
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In lab experiments on mice, researchers observed how cellular waste was flushed out via the brain's blood vessels into the body's circulatory system and eventually the liver.
These waste products included amyloid beta, a protein that when accumulated is a driver of Alzheimer's disease.
In order to help remove the waste, cerebral spinal fluid is pumped through brain tissue.
![Obstructive Sleep Apnea]( "Obstructive Sleep Apnea")
Obstructive sleep apnea should be suspected in overweight middle aged adults who snore loudly and which can cause interruption of breathing for 10 seconds or more and this results in reduced blood o
The process is sped along during sleep because the brain's cells shrink by about 60 percent, allowing the fluid to move faster and more freely through the brain.
The whole operation takes place in what researchers call the glymphatic system, which appears to be nearly 10 times more active during sleep than while awake.
"The brain only has limited energy at its disposal," said lead author Maiken Nedergaard of the University of Rochester Medical Center.
"You can think of it like having a house party. You can either entertain the guests or clean up the house, but you can't really do both at the same time."
Co-authors of the study, which was funded by the US National Institutes of Health, came from Oregon Health and Science University and New York University.
Source: AFP
In order to help remove the waste, cerebral spinal fluid is pumped through brain tissue.
Obstructive Sleep Apnea
Obstructive sleep apnea should be suspected in overweight middle aged adults who snore loudly and which can cause interruption of breathing for 10 seconds or more and this results in reduced blood o
Advertisement
The process is sped along during sleep because the brain's cells shrink by about 60 percent, allowing the fluid to move faster and more freely through the brain.
The whole operation takes place in what researchers call the glymphatic system, which appears to be nearly 10 times more active during sleep than while awake.
"The brain only has limited energy at its disposal," said lead author Maiken Nedergaard of the University of Rochester Medical Center.
"You can think of it like having a house party. You can either entertain the guests or clean up the house, but you can't really do both at the same time."
Co-authors of the study, which was funded by the US National Institutes of Health, came from Oregon Health and Science University and New York University.
Source: AFP
Circadian Rhythm Sleep Disorders
Circadian rhythm (also known as sleep/wake cycle or the body clock) is a biological process that follows an internal cycle of roughly 24 hours.
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 Periodic Limb Movement DisorderPeriodic limb movement disorder (PLMD) is a sleep disorder which causes repetitive cramping or jerking of the legs, resulting in disturbance of sleep. | Advertisement
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