Wipl phosphatase, an enzyme may be a potential target that will help stop the spread of cancer
Although studies in the past have revealed that this enzyme plays a critical role in regulating the budding of tumours, scientists have for the first time unearthed a mechanism for its mode of action.
Dr Dmitry Bulavin and his team at A*STAR's Institute of Molecular and Cell Biology (IMCB), discovered that Wip1 phosphatase is a key factor that causes point mutations to sprout in human cancers.
These types of mutations stem from errors that are made during DNA replication in the body, causing one base-pair in the DNA sequence to be altered.
This is a ground-breaking finding that sheds light on how mutations in cancer can potentially be wiped out with drugs, allowing cancers to be treated and eliminated effectively, preventing relapses of tumour growth.
The study has been published in the scientific journal, Cancer Cell.