Two sisters from Mount Horeb in Wisconsin, United States, have filed a case in a federal court in Washington DC, claiming that a cervical cancer vaccine led to premature ovarian failure which has made it impossible for them to get pregnant.
Madelyne Meylor, 20, and Olivia Meylor, 19, claimed that their premature ovarian failure has been caused by Gardasil, a vaccine against human papillomavirus (HPV) developed by Merck. Their attorney, Mark Krueger, said that theirs was the first complaint that the vaccine caused the condition to reach a hearing through the National Vaccine Injury Compensation Program.
Madelyne revealed that she had her first menstrual periods at the age of 13 years, a few months before she took her first dose of the HPV vaccine. Her periods started to become irregular after each dose before they completely stopped soon after taking the third dose at the age of 15 years while Olivia had her final period at the age of 16.
Doctors though have questioned the claims while Merck has released a statement in which they said that there were no reports of premature ovarian insufficiency (POI) in their clinical trials with Gardasil.
"Merck has reviewed the post-licensure reports of POI after administration of Gardasil and has concluded that the evidence does not support a causal relationship to the vaccine. The cases have been reported to the U.S. FDA and other regulatory agencies. There have been no reports of POI in the clinical trials with Gardasil", Merck said.