Physical Fitness and Lower Aortic Stiffness Linked to Slower Brain Aging

Physical fitness and lower aortic stiffness may be associated with slower brain aging, reports a new study. The findings of the study are published in the Journal of Alzheimer's Disease.

The rate of decline in certain aspects of memory may be explained by a combination of overall physical fitness and the stiffness of the central arteries, researchers from Swinburne's Centre for Human Psychopharmacology have found.

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‘Physical fitness and more elastic aorta may protect cognitive function, by reducing the negative effects of excessive blood pressure on the brain. Therefore, staying physically fit and monitoring central arterial health may be a valuable, cost-effective way to maintain our memory and other brain functions in older age.’

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A study considers the mechanisms underlying cognitive performance in older people living independently. Lead author, Ph.D. candidate Greg Kennedy, says that from early adulthood, memory and other aspects of cognition slowly decline, with an increased risk of developing into dementia in later life.

"Exactly why this occurs is unclear, but research indicates that exercise and physical fitness are protective," Mr. Kennedy says. "A healthier, more elastic aorta is also theorized to protect cognitive function, by reducing the negative effects of excessive blood pressure on the brain."

The study investigated whether fitness was associated with better cognition through a healthier aorta. Physical fitness and arterial stiffness assessment One hundred and two people (73 females and 29 males), aged between 60 and 90 years, living independently in aged care communities, were recruited in Melbourne, Australia.

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Their fitness was assessed with the Six-Minute Walk test which involved participants walking back and forth between two markers placed 10 meters apart for six minutes.

Only participants who completed the full six minutes were included in the analysis, which assessed the stiffness of their arteries and cognitive performance.

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"People generally are less fit and have stiffer arteries as they age, which seems to explain the difference in memory ability that is usually attributed to 'getting older,'" Mr. Kennedy says.

Interestingly, physical fitness did not seem to affect central arterial stiffness, however, Mr. Kennedy points out that only current fitness was assessed - long-term fitness may be a better predictor of central arterial stiffness, however, this has yet to be investigated.

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"Unfortunately, there is currently no effective pharmacological intervention that has proven effective in the long term in reducing this decline or staving off dementia," Mr. Kennedy says.

"The results of this study indicate that remaining as physically fit as possible, and monitoring central arterial health, may well be an important, cost-effective way to maintain our memory and other brain functions in older age."

Source-Eurekalert