About My Health Careers Internship MedBlogs Contact us

Pediatric Atrial Fibrillation Has High Recurrence Rates

by Bidita Debnath on October 11, 2013 at 10:12 PM
Font : A-A+

 Pediatric Atrial Fibrillation Has High Recurrence Rates

Atrial fibrillation (AF) is the most common chronic arrhythmia in adults, but is rare in children. It is characterized by a rapid and irregular heartbeat.

In one of the first studies of pediatric "lone AF" (AF without associated heart disease), researchers found a nearly 40% recurrence rate and that AF in the young is accompanied by substantial symptoms. Three patients had significant complications: one with a stroke and two with substantially impaired heart function. The researchers' findings are published in the October issue of the Canadian Journal of Cardiology.


"Large population studies of adult patients with lone AF have found that the cumulative rate of progression to permanent AF is 19% at ten years and 29% at 30 years, but there are no similar data published for younger patients. Longer term follow-up studies of pediatric patients with lone AF are required to better understand the natural history specific to this population," says lead investigator Shubhayan Sanatani, MD, Associate Professor, Division of Pediatric Cardiology, University of British Columbia, Vancouver.

Lone AF is defined as occurring in patients with AF who are less than 60 years of age and do not suffer from other forms of cardiovascular disease or hypertension. Lone AF in younger patients is rare and constitutes less than 5% of all types of AF.

Four centers from the Canadian Pediatric Electrophysiology Working Group (Vancouver, Toronto, Edmonton, and Ottawa) identified patients eligible for the current study, which resulted in the largest cohort of pediatric lone AF to date. Investigators reviewed records from 1996 to 2011 and identified 42 patients with a first episode of lone AF. Four patients were later categorized as having persistent AF. Patients with AF in the setting of thyroid disease, ventricular pre-excitation, coexisting congenital heart disease, or a history of cardiac surgery were excluded. Thirty-one of the patients were male, and the median age at first presentation was 15 years.

The investigators sought to describe the clinical characteristics, management strategies, and recurrence rates and to identify factors that might predict AF recurrence. They found that AF recurred in 15 of 38 patients (39%) and the time to estimated recurrence was 19 months. Factors predictive of recurrence included longer duration of the initial episode and the reporting of frequent palpitations (daily or weekly) after the initial episode. Three patients had AF-related complications.

There was a wide variation in management strategies used in both the acute treatment and outpatient management of AF, particularly in the treatment of the initial presenting episode.

Sex, age, family history, size of the left atrium, and a history of cardioversion (a procedure that can "shock" certain abnormal rhythms back to a normal rhythm) were not associated with recurrence. Excluding patients with persistent AF, recurrence with another supraventricular tachyarrhythmia (SVT) was observed in 6 of 38 (16%) patients, which is possibly a predisposing factor for AF. Twelve patients underwent electrophysiology (EP) study, with six patients receiving ablation.

"In conclusion, although it appears to be a rare disease in pediatric patients, lone AF does carry a substantial burden of symptoms and has a high recurrence rate," comments Dr. Sanatani. "Our reported rate of recurrence of 39% is important when counseling pediatric patients and their families on the expected course and treatment goals. The specific management strategies in pediatric patients have still not been well defined, but there is a need for an organized and consistent approach. Pediatric practice should be in alignment with published adult guidelines. Long-term follow-up studies and larger series of pediatric patients with lone AF are required to better understand the natural history," he concludes.

Source: Eurekalert

News A-Z
News Category
What's New on Medindia
Is COVID-19 Vaccination during Pregnancy Safe?
Sensory Processing Disorder (SPD)
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Palpitations And Arrhythmias Pediatric Pyloric Stenosis Atrial Fibrillation Cardiac Ablation Drugs for Atrial Fibrillation 

Recommended Reading
Research Finds That Women With Atrial Fibrillation Under-treated by GPs
Women with atrial fibrillation (AF) under-treated by general practitioners (GPs), finds new ......
Mass Screening Identifies Untreated Atrial Fibrillation in 75-76 Year Olds
The second cause of death worldwide is stroke. Atrial fibrillation is the most common clinically ......
Association Between Fish Consumption and Atrial Fibrillation Reveals U-shaped Curve
According to an observational study moderation seems to be key when it comes to eating fish to ......
Paroxysmal Atrial Fibrillation Patients Should Undergo Depression Screening
A new study reveals that patients suffering from paroxysmal atrial fibrillation (AF) displayed ......
Atrial Fibrillation
Atrial fibrillation may not be life-threatening in itself but it is important to understand the caus...
Cardiac Ablation
Cardiac Ablation is a minimally invasive heart procedure, which involves identifying and scarring th...
Drugs for Atrial Fibrillation
Atrial fibrillation is a condition with irregular heart rhythm. Be aware of the prescribed drugs, th...
Palpitations And Arrhythmias
Palpitations are unpleasant sensation of one’s own heartbeat....
Pediatric Pyloric Stenosis
Pyloric stenosis in a child is narrowing of the pylorus due to which the milk cannot pass into the s...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use