The most comprehensive genomic analysis of prostate cancer has been developed by scientists who hope this will help to develop patient subgroups and in making individual treatment decisions.
"One of the holy grails of prostate cancer is to identify which tumors need to be aggressively treated and which don't. Ultimately, what we have learned could lead to the creation of a genetic-based test to determine which prostate cancers might become more virulent and require aggressive treatment and which tumors may not," said senior study author Charles Sawyers, from Memorial Sloan-Kettering Cancer Center (MSKCC).
Quiz on Prostate Cancer
Prostate cancer is fast gaining as a common cancer form among men; more threatening since its symptoms often go unnoticed until it's too late. This quiz tests your knowledge on prostate cancer, its diagnosis and treatment options and is as mandatory for men as the screening tests mentioned here are!
Advertisement
The difference between aggressive treatment and a "wait and watch" approach has obvious quality-of-life implications for prostate cancer patients.
The MSKCC team used an integrated, comprehensive approach to analyze 218 primary and metastatic samples and 12 cell lines. All samples were procured from patients treated by radical prostatectomy at MSKCC.
![Genetic Testing of Diseases]( "Genetic Testing of Diseases")
Genetic testing helps to confirm a genetic condition in an individual and involves q complex laboratory techniques
The analysis revealed a much higher frequency of alterations in the androgen receptor pathway than previously suspected. Also, the pattern of DNA copy number alterations identified defined subsets of low-and high-risk disease beyond what is revealed by Gleason score.
The study has been published early online on June 24 in the journal Cancer Cell.
Source: ANI
Genetic Testing of Diseases
Genetic testing helps to confirm a genetic condition in an individual and involves q complex laboratory techniques
Advertisement
The analysis revealed a much higher frequency of alterations in the androgen receptor pathway than previously suspected. Also, the pattern of DNA copy number alterations identified defined subsets of low-and high-risk disease beyond what is revealed by Gleason score.
The study has been published early online on June 24 in the journal Cancer Cell.
Source: ANI
Advertisement
Advertisement
|
Advertisement
Recommended Reading
Latest Cancer News
Chronotherapy (the sleep-wake cycle) is observed as a valuable alternative treatment in cancer diagnosis and treatment.
A nanoengineering platform targets neutrophils, the white blood cells without killing pancreatic cancer cells paving the way for effective treatments.
The survival rates between lobectomy and wedge resection surgical procedures were found to be the same among lung cancer patients.
The mechanism by which the kinases cause inflammation has been discovered by scientists.
Pancreatic cancer cases are on the rise. The biomarker approach could reduce the chance of developing pancreatic cancer.