Genetic mutations with an impact on long-term health have been noticed in children born to non-smoking mothers, reveals a study done at University of Pittsburgh Graduate School of Public Health.
The abnormalities, which were indistinguishable from those found in newborns of mothers who were active smokers, may affect survival, birth weight and lifelong susceptibility to diseases like cancer, the study revealed.
The study confirmed previous research in which study author Stephen G. Grant, associate professor of environmental and occupational health at Pitt's Graduate School of Public Health, discovered evidence of abnormalities in the HPRT gene located on the X chromosome in cord blood from newborns of non-smokers exposed to environmental tobacco smoke.
"These findings back up our previous conclusion that passive, or secondary, smoke causes permanent genetic damage in newborns that is very similar to the damage caused by active smoking," Dr. Grant said.
"By using a different assay, we were able to pick up a completely distinct yet equally important type of genetic mutation that is likely to persist throughout a child's lifetime. Pregnant women should not only stop smoking, but be aware of their exposure to tobacco smoke from other family members, work and social situations," he added.
The study was published in the online Open Pediatric Medicine Journal.