In his study, Salman Hyder, a University of Missouri researcher, exposed rats with a certain type of breast cancer to apigenin, a common compound found in parsley, celery, apples, oranges, nuts and other plant products.
The rats that were exposed to the apigenin developed fewer tumors and experienced significant delays in tumor formation compared to those rats that were not exposed to apigenin. Hyder believes this finding could impact women who are taking certain hormone replacement therapies.
"We know that certain synthetic hormones used in HRT accelerate breast tumor development. In our study, we exposed the rats to one of the chemicals used in the most common HRTs received in the United States - a progestin called medroxyprogesterone acetate (MPA) - which also happens to be the same synthetic hormone that accelerates breast tumor development."
Hyder also found that the compound reduced the overall number of tumors. However, while apigenin did delay tumor growth, it did not stop the initial formation of cancer cells within the breast.
Hyder said researchers have not identified a apigenin dosage for humans yet.However, it appears that keeping a minimal level of apigenin in the bloodstream is important to delay the onset of breast cancer that progresses in response to progestins such as MPA," Hyder said.
It's probably a good idea to eat a little parsley and some fruit every day to ensure the minimal amount," he added.
The study was published recently in Cancer Prevention Research.
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