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Once-promising Genital Herpes Vaccine Fails in a Large Clinical Trial

by Dr. Trupti Shirole on January 5, 2012 at 3:11 PM
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 Once-promising Genital Herpes Vaccine Fails in a Large Clinical Trial

A once-promising genital herpes vaccine has failed in a large clinical trial, reported researchers. Researchers found that the vaccine efficacy was only 20%.

About 8,300 uninfected women, aged 18-30 years, were part of this new study. Researchers found that the experimental genital herpes shot was only mildly effective against herpes simplex virus type 1 (HSV-1), which commonly causes cold sores and sometimes genital herpes; and not at all effective against herpes simplex virus 2 (HSV-2), the most common cause of genital herpes.

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Study co-author Dr. Peter Leone said, "We will need to take a 'different type of vaccine approach' in order to find something that works against both viruses."

The study is published in the New England Journal of Medicine.

Source: Medindia
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