Apart from being a 'feel good' brain messenger, the spontaneous impulses of dopamine in mice have shown that the animal can willfully manipulate these random dopamine pulses.

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Apart from being a 'feel good' brain messenger, the spontaneous impulses of dopamine in mice have shown that the animal can willfully manipulate these random dopamine pulses. This opens a new dimension in the study of dopamine and brain dynamics.
A feedback scheme was designed by the team to investigate if these impulses are occurring in the mice. The animal was trained to receive a reward on a treadmill if they show that they were able to control the impromptu dopamine signals.
It was found that the mice, apart from being aware of these dopamine impulses, also learned to anticipate and volitionally act upon a portion of them.
"Critically, mice learned to reliably elicit (dopamine) impulses prior to receiving a reward. These effects reversed when the reward was removed. We posit that spontaneous dopamine impulses may serve as a salient cognitive event in behavioral planning," says the researchers in the paper.
The study thereby opens a new dimension in the study of dopamine and brain dynamics, stating that dopamine appears to invigorate, rather than initiate, motor behavior.
Source-Medindia
MEDINDIA



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