New findings could lead to effective preventive and therapeutic treatments in people with heart disease and/or gum disease without unwanted side effects.
New Technique To Identify Plaque In Peripheral Atherosclerosis
Peripheral atherosclerosis is a common circulatory problem in which narrowed arteries reduce blood flow to your limbs and causes pain in the legs.
Peripheral atherosclerosis is a common circulatory problem in which narrowed arteries reduce blood flow to your limbs and causes pain in the legs.
‘Effective preventive and therapeutic treatments in people with heart disease and/or gum disease are rare. Resolvin E1 therapy could provide a very effective and safe therapy that can be taken daily.’
Resolvin E1, a molecule produced naturally in the body from an omega -3 fish oil, topically applied on gum tissues not only prevents and treats gum disease as previously shown (Hasturk et al 2006 and 2007), but also decreases the likelihood for advanced arterial atherosclerotic plaques to rupture and form a dangerous thrombus or blood clot. The findings, which appear in the journal Current Atherosclerosis Reports, could lead to effective preventive and therapeutic treatments in people with heart disease and/or gum disease without unwanted side effects.
To test the effectiveness of lipid mediators on advanced atherosclerosis, researchers from Boston University School of Medicine (BUSM) and The Forsyth Institute used two groups of an experimental model that possessed highly inflamed advanced atherosclerosis. The first group was treated with a solution applied on gum tissues that contained Resolvin E1 while the second group was treated with salt water as a control. The group treated with the inflammation-lowering lipid mediator (Resolvin E1) had minimal atherosclerosis and reduced plaque rupture in their aortic artery, while atherosclerosis advanced to more severe form of the disease in the control (salt water) group.
Marathons Not Linked to Atherosclerosis Risk
Studies have linked risk of atherosclerosis in marathon runners. But a new research has found that marathon does not increase the risk of atherosclerosis.
Studies have linked risk of atherosclerosis in marathon runners. But a new research has found that marathon does not increase the risk of atherosclerosis.
The researchers believe these findings support a paradigm shift in the treatment of both localized and systematic inflammatory conditions that are increasingly prevalent in type 2 diabetes and obesity and may be applicable to other chronic inflammatory diseases.
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Aspirin Drug May Not Benefit Patients With Atherosclerosis
Aspirin is commonly used for treating cardiovascular problems. It may provide little or no benefit for certain patients with atherosclerosis, finds a new study.
Aspirin is commonly used for treating cardiovascular problems. It may provide little or no benefit for certain patients with atherosclerosis, finds a new study.
Senescent Cells Linked To Atherosclerosis Progression
Using three mouse models Mayo Clinic scientists discovered that senescent cells have negative effects at all three stages of the disease process.
Using three mouse models Mayo Clinic scientists discovered that senescent cells have negative effects at all three stages of the disease process.
