About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

New Test to Distinguish Psoriasis from Eczema Identified

by Sheela Philomena on July 12, 2014 at 2:52 PM
Font : A-A+

 New Test to Distinguish Psoriasis from Eczema Identified

Researchers have developed a new diagnostic procedure which in practice enables psoriasis and eczema to be reliably differentiated from one another on the basis of only two genes.

A better understanding of molecular processes

Advertisement

"Both diseases have a highly complex appearance, which often varies widely from one patient to another," says Dr. Stefanie Eyerich, who heads the Specific Immunology working group at the Institute of Allergy Research (IAF) at the Helmholtz Zentrum München. "This has led previous attempts to compare their molecular signature to fail." In this study, the researchers identified 24 patients who were suffering simultaneously from psoriasis and eczema and in each analyzed at the molecular level the characteristic differences they demonstrated between psoriasis and eczema compared to clinically unremarkable skin.

"We were thus able to drastically reduce random genetic or environmental influences and gain a detailed picture of the development of these two diseases," explains Prof. Fabian Theis of the Institute of Computational Biology (ICB) at the Helmholtz Zentrum München.
Advertisement

Paving the way for personalized medicine

In recent years, many new specific treatments have been developed for psoriasis and eczema. However, in each case, these are only effective for one or other of the two diseases. And they are very expensive: one such treatment generally costs several tens of thousands of euros per year, per patient. The ability to make an exact diagnosis therefore has a considerable economic impact.

If it cannot be clearly determined on presentation which of the two diseases is involved, the newly developed diagnostic tool will help to differentiate them. It involves a test which compares samples of diseased and healthy skin and is concluded within one day. The researchers have now filed a patent application for it.

The procedure, moreover, marks the first step towards the introduction of personalized medicine also for chronic inflammatory skin diseases. "Whereas this is practiced increasingly in oncology, for example in the form of mutation analyses and the subsequent decision in favor of the best individual treatment option, it is not common in the case of inflammatory skin diseases," says Kilian Eyerich of the Clinic and Polyclinic for Dermatology at the Technical University of Munich.

The researchers plan to purse this path with a view to characterizing even more precisely the molecular processes involved in inflammatory skin diseases and combining them with clinical information, such as the choice of certain treatments. In this way, their goal is to determine the best possible treatment option for each individual patient.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Contraceptive Pills in Polycystic Ovary Syndrome (PCOS) Curtail Type 2 Diabetes Risk
Mushroom May Help Cut Down the Odds of Developing Depression
How to Battle Boredom during COVID
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Allergy Skin Disorder Atopic Dermatitis Psoriasis Varicocele Types of Food Allergies Dry Skin Symptom Evaluation Foods that are Bad for your Skin Testicle Pain - Symptom Evaluation Itchy Scalp 

Recommended Reading
Psoriasis
Psoriasis is a recurrent and complex inflammatory skin disorder that can have tremendous physical .....
Skin Disease
Skin diseases also known as dermatologic disorders are many in number and so are their causes. The ....
Atopic Dermatitis
Atopic dermatitis is an inflammatory, non-contagious, chronic skin disorder that involves scaly and ...
New Experimental Medication Shows Promise in Tackling Eczema
A new study has found that a new medication may be potent enough to treat the most common skin ......
Allergy
An allergy is a hypersensitive disorder of immune system. Substances that often cause allergic react...
Dry Skin Symptom Evaluation
Dry skin a result in inadequate hydration of the skin. This could be either due to a reduced intake...
Foods that are Bad for your Skin
Hydration, sebum formation and skin acidity determine the skin condition. Along with aging and envir...
Skin Disorder
Skin types can range from oily to dry, extreme dryness accompanied by rashes and itching can often d...
Testicle Pain - Symptom Evaluation
A sudden, severe pain in the testis may be due to testicular torsion. Testicles inside the scrotum a...
Types of Food Allergies
If you are allergic to certain food items-Watch out for what you eat...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use