New Recreational Drug Flakka as Potent, Addictive as Bath Salts

by Shirley Johanna on May 13, 2015 at 6:26 AM
Font : A-A+

New Recreational Drug Flakka as Potent, Addictive as Bath Salts

A New recreational drug alpha-PVP (flakka) is found to be equivalently potent as a stimulant and addictive as MDPV (bath salts), says a new research.

News stories in recent months have blamed flakka for incidents of extreme violence, paranoid psychoses, compulsive nudity, zombie-like behavior and even "superhuman strength".


The Scripps Research Institute (TSRI) Associate Professor Tobin J. Dickerson, who was co-senior author of the study said that it doesn't mean that flakka use is safe and in their data show that flakka is as potent as MDPV, making it a very good stimulant, arguably with worse addiction liability than methamphetamine.

For the study, the research team used a standard animal model of addiction potential in which rats are trained to press a lever to infuse themselves intravenously with small doses. As expected for an addictive stimulant, the rats tended to press the drug-delivery lever more and more in each one-hour session as 20 daily sessions progressed. When the researchers increased the number of lever presses required to get another dose, the animals kept pressing for up to hundreds of presses per dose.

Michael A. Taffe, an associate professor at TSRI, said that they commonly think of drug addiction as making the drug more important than anything else in the user's life, but they haven't had good rodent models of that and the animals will almost always respond more to food and tasty flavors, for example, than drugs.

Remarkably, a subset of the rats didn't increase their MDPV intake gradually, but went from occasional sampling to bingeing on as much as they could get during the session.

MDPV is related to cathinone, a natural stimulant found in the khat leaves traditionally chewed in Northeast Africa and Arabian Peninsula regions, but it also shares structural similarity to methamphetamine and MDMA. Originally developed as a potential pharmaceutical stimulant by Boehringer Ingelheim chemists in the 1960s, MDPV re-emerged as a recreational drug within the past decade.

Taffe added that there were now dozens of substituted cathinones out there that could become popular, and what they were trying to do was to study these drugs as they emerge, using our animal models, and hopefully come up with general principles for predicting their effects.

The study is published online ahead of print in the journal Psychopharmacology.

Source: Medindia

News A-Z
News Category
What's New on Medindia
World Alzheimer's Day 2021 - 'Know Dementia, Know Alzheimer's
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
Stroop Effect
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drug Toxicity Signature Drug Toxicity Recreational Drugs are not Completely Safe 

Recommended Reading
Trending as New Bath Salt Drugs Are 'Designer Stimulants'
A new drug problem in so-called "bath salts"-actually "designer stimulants," packaged and sold in .....
Use of Psychotropic Medication Including Stimulants, in Young Children Leveling Off
In very young children, the use of psychotropic prescription medications to treat ADHD, mood ......
Risk of Cardiac Events in Youth Not Increased by Stimulant Treatment for ADHD
Stimulant medications, such as methylphenidate and amphetamine products, are used to treat ......
New Stimulants Could be Developed from Dreaming, Waking Brain Mechanisms
A new study says that scientists may be able to develop more effective anaesthetics and ......
Drug Toxicity
Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a d...
Recreational Drugs are not Completely Safe
Recreational drugs are commonly used in rave parties. Serotonin syndrome can occur in patients takin...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use