New Hormone Therapies are Beneficial for Hot Flashes

Hormone therapy is the best proven method for the management of menopause symptoms such as hot flashes. However, research continues to identify the novel trajectories to estrogen therapy that minimize any associated risks.

Dr. Hugh Taylor //from Yale School of Medicine will discuss some of the latest developments, including fetal estrogens, during the 2020 Pre-Meeting Symposium of The North American Menopause Society (NAMS).

About Hot Flash
The frequency of the hot flash can be from 1 to 2 two hot flashes a week to 10 or greater in a day. The silver lining is that it usually decreases over time.

‘It is important for healthcare providers to understand that selective estrogen receptor modulators and estrogens have different biological characteristics, and some may even have benefits over others, increasing the opportunities for personalizing care for women.’

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According to Dr. Taylor, a number of enhancements have been introduced in the past decade including new selective estrogen receptor modulators (SERMs) and the use of estrogens together with SERMs to replace progestins.

Fetal estrogens constitute one of the newest promising developments. Their unique properties differentiate them from estradiol, inspite of the fact that they have some SERM-like properties.

Dr. Taylor illustrated that estriol and estetrol have entered clinical use with new data showing favorable characteristics. Particularly, estetrol declines hot flashes and leads to favorable cardiovascular changes while preventing estradiol stimulation of the breast.

Menopause and Sex - Symptoms, Signs, Natural remedies
Menopause occurs when a woman's ovaries stop producing the hormone estrogen. Since estrogen is linked to sex drive, a woman will experience changes in sexual desire around the time of menopause.

Estriol acts as a weak estrogen but can still prevent some negative effects of estradiol.

"In addition to the already-established benefits, there is also reason to believe that these fetal estrogens may provide added benefits that have yet to be fully explored, making them even more promising," says Dr. Taylor.

Perimenopause - Causes, Symptoms, Diagnosis and Treatment
Perimenopause is a transition phase that lasts until menopause. The low estrogen levels during this phase cause irregular periods and early menopause symptoms such as hot flashes. This phase may last from a few months to years.

"This presentation promises to offer some great insights into the future of hormone therapy," says Dr. Stephanie Faubion, NAMS medical director.

Source-Medindia