Liver regeneration can be spurred after surgery with a newly found drug, as published in a paper in The Journal of Experimental Medicine. Liver cancer often results in a loss of blood flow and thus oxygen and nutrients to the liver tissue, resulting in deteriorating liver function. Although the diseased part of the liver can often be surgically removed, the sudden restoration of blood flow to the remaining liver tissue can trigger inflammation—a process known as ischemia reperfusion injury (IRI). IRI results in part from the deposition of immune proteins called complement on the surface of liver cells, causing them to die and thus impairing liver regeneration. Complement inhibitors effectively dampen IRI, but the benefits of this approach come at a cost, as certain complement proteins are also required for liver tissue to regrow. A group of scientists at the Medical University of South Carolina now show that a novel complement inhibitor reduces complement-mediated liver cell death and actually stimulates post-surgery liver regrowth in mice. The novel inhibitor limited the deposition of complement proteins and promoted the division of new liver cells. Even after removal of as much as 90% of the liver, treatment increased survival from 0% in untreated animals to an impressive 70%. The selectivity of this novel complement inhibitor, and its unexpected ability to promote liver regeneration, suggests that it might represent a new treatment strategy for a variety of liver injuries in humans. Source: Eurekalert << New Mechanism of Osteoarthritis Identified by Research on a... New Way to Manipulate Malaria Genes Identified >> Recommended Reading Quiz on Liver How many of us know that the liver is a vital organ the size of an American Football? To understand more about the liver and its functions spend a few minutes taking part in this ... READ MORE Liver Cancer - Animation Liver is the largest organ inside the human body. It performs 500 different functions and processes 720 liters of blood per day. The important functions of the liver, the development of liver cancer and it's symptoms are presented in this ... READ MORE Liver Cancer Treatment - Animation Liver Cancer is the uncontrolled growth of cells in the liver. The present section provides a graphic description of the various forms of liver cancer treatment in addition to the latest techniques such as Chemoembolisation and Radio frequency ... READ MORE Clinical Trials - Different Phases of the trial Clinical trials serve as a vital component for improving the treatment of medical conditions as they lead to higher standards of patient care. READ MORE Current Treatments for Liver Cancer Current Treatments for Liver Cancer (also known as hepatoma or hepatocellular carcinoma) can result in complete cure of the disease if it is detected early. READ MORE Drug Toxicity Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a drug, reaction to a drug or drug abuse. READ MORE Fatty Liver Disease: A Growing Health Problem in India Non alcoholic fatty liver disease (NAFLD) is the leading cause of liver dysfunction worldwide and is a rapidly growing health problem in India. READ MORE Hepatitis A Hepatitis A is the most benign of the hepatitis viruses and usually has no long term side effects. Hepatitis A vaccine is available that is 95% effective in preventing the disease. READ MORE Living Donor Liver Transplant: What Are the Risks? The risk of dying as a result of a living donor liver segment removal is between 0.2-2.0%. The risk of morbidity is anywhere between 1.3% (in highly experienced centers) to 60%. READ MORE Milk Thistle Milk Thistle is a resourceful natural plant which has many medicinal benefits. In herbal medication milk thistle is used in cases of liver diseases. READ MORE Wilson's Disease This is a rare inherited systemic disorder of copper metabolism, affecting the liver mainly before other organs. READ MORE Most Popular on Medindia Daily Calorie Requirements Blood Donation - Recipients Calculate Ideal Weight for Infants More News on: Drug ToxicityHepatitis AClinical Trials - Different Phases of the trialSignature Drug ToxicityLiverWilson's DiseaseMilk ThistleCurrent Treatments for Liver CancerFatty Liver Disease: A Growing Health Problem in IndiaLiving Donor Liver Transplant: What Are the Risks?