New Device-Based Therapy Reduces Severe Asthma Attacks

Bronchial thermoplasty offers an alternative approach for patients who are inadequately controlled with medications to improve the control of their asthma.

Bronchial thermoplasty (BT), is a new device-based therapy approved by the FDA in 2010 and uses a series of three radio-frequency treatments to open the airways of adults with severe, persistent asthma.

In a new study presented at the //2017 American Thoracic Society International Conference, adult asthma patients treated with bronchial thermoplasty (BT) had fewer severe exacerbations and were able to reduce their ER visits and hospitalizations in the two years following treatment.

Asthma - Factors, Common Allergens, Diagnosis, Treatment, Support Groups, FAQs
It's a lung condition characterized by inflammation of the bronchi and constriction of the airways that result in coughing, wheezing or breathlessness. Allergy and other airway irritants can trigger it

‘Bronchial thermoplasty proves effective to open the airways of adults with severe, persistent asthma whose symptoms are not adequately controlled by inhaled corticosteroids or long-acting beta-agonists.’

To date, more than 6,800 patients in 33 countries have been treated with BT. The "Post-FDA Approval Clinical Trial Evaluating BT in Severe Persistent Asthma" (PAS2 study), which involves hundreds of patients at dozens of research centers, looks at the long-term effects and safety of BT.

"The results of the PAS2 study suggest that after a single series of BT procedures, patients experience long-term improvement in their asthma control," said lead author Geoffrey Chupp, MD, from Yale School of Medicine.

"These results indicate that BT works across the spectrum of severe asthma patients. We believe BT should be more widely considered as a treatment option in patients with poorly controlled severe asthma."

Tests for Asthma - Medical and Family History, Diagnosis & Treatment
Do you find it difficult to breathe especially during the cold weather? You may need to get tested for asthma, a respiratory condition that is induced by allergies.

Two-hundred eighty four patients were enrolled in the study at 27 centers in the U.S. and Canada. Two-hundred seventy-nine study subjects had at least one BT procedure, and 271 had all three procedures.

In the 12 months prior to the first BT procedure, 78 percent of subjects had at least one severe exacerbation, 16 percent required hospitalization and 29 percent had ER visits.

Respiratory Diseases - Diseases of the Human Respiratory System
Respiratory diseases affect any part of the respiratory system. Some of the lung diseases like chronic obstructive pulmonary disease can lead to respiratory failure.

In the first year follow up, 50.6 percent had severe exacerbations; 45.4 percent had exacerbations in the second year follow up.

Asthma-related hospitalizations and ER visits also saw significant, continuing reductions: 14.4 percent and 12.7 percent of subjects had hospitalizations, respectively, in the first and second year, and 18.3 percent and 13.5 percent made ER visits in the first and second year post-treatment.

Air Conditioner Health Hazards
This section gives a brief introduction about what air conditioner health hazard means and what kind of people get affected by it, and what causes them.

"On average, patients also reduced their inhaled corticosteroid dose and a significant number were able to discontinue maintenance oral corticosteroids," said Dr. Chupp.

"BT offers an alternative approach for patients who are inadequately controlled with medications designed to improve the control of their asthma."

Source-Eurekalert