About Careers MedBlog Contact us

RoseHip Extract Enhances the Ability of Chemotherapy Drug Used for Breast Cancer

by Julia Samuel on April 28, 2015 at 5:47 PM
Font : A-A+

RoseHip Extract Enhances the Ability of Chemotherapy Drug Used for Breast Cancer

The extract of RoseHip, the fruit of the rose plant shows promising results for preventing breast cancer, reports a new study. Rosehip, the round part of the rose flower located just below the petals, are used as a natural source of vitamin C in tea and other foods.

Triple negative, a type of breast cancer showed reduced growth and migration of cells after they were treated with the extract. This particularly aggressive form of cancer does not respond to most available treatments and tends to affect young women as well as those who are African-American or Hispanic.


For the experiments, the researchers used pure rosehip, which can be purchased as a supplement in pill or liquid form. The scientists treated tissue cultures of triple negative breast cancer cells with several concentrations of rosehip extract. Exposure to the highest concentration (1.0 mg/ml) decreased triple negative breast cancer cell proliferation by 50%.

The effect was reduced with decreasing concentrations. The highest concentrations of rosehip extracts (.025 to 1.0 mg/ml) decreased triple negative breast cancer cell migration by 25 to 45%. Additional experiments revealed that the extract appears to work by reducing Mitogen activated protein kinases (MAPK) and Protein kinase B/Akt, two enzymes that are known to promote cell growth in triple negative breast cancer.

The extract also enhanced the ability of the commonly used breast cancer chemotherapy drug doxorubicin to decrease cell proliferation and migration in the tissue cultures, suggesting rosehip extract might be a beneficial addition to the overall treatment regimen for patients with triple negative breast cancer.

The breast cancer research grew out of previous studies in which the investigators used rosehip extract to successfully prevent cancer cell growth in the brain, one of the places to which triple negative breast cancer tends to spread. They would also like to test the extract's effects on prostate cancer cells.

Source: Medindia


Recommended Reading

Latest Cancer News

Cancer Drugs to be Tested in Orbit During American Private Astronaut Mission
The mission of Axiom Space incorporated numerous experiments focusing on human stem cell aging, inflammation, and cancer within the laboratory situated in the low Earth orbit.
 Hydrogen Sulfide Makes Cancer Cells More Sensitive to Photothermal Therapy
Providing a sustained supply of hydrogen sulfide to cancer cells, could be a remodeling strategy to improve photothermal therapy efficacy while minimizing side effects.
Hidden Influence of Gut Microbiome on Early-Onset Colorectal Cancer
Colon cancer's hidden link revealed in microbiome study.
Telephone-based Weight Loss Program Helps Breast Cancer Patients Shed Pounds
Breast cancer patients in the obese or overweight category can greatly benefit from a telephone-based weight management program in achieving significant weight loss.
 Tobacco Use Among Cancer Patients Likely to Increase Symptom Burden
A new study assessed the association of cigarette smoking and vaping on cancer-related symptom burden (fatigue, pain, emotional problems) and quality of life.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

RoseHip Extract Enhances the Ability of Chemotherapy Drug Used for Breast Cancer Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests