A novel nanoparticle-based technique developed by researchers helps detect pathogens associated with inflammatory bowel disease.
The new nanoparticle-based technique also may be used for detection of other microbes that have challenged scientists for centuries because they hide deep in human tissue and are able to reprogram cells to successfully evade the immune system.
Crohns Disease
Crohn's disease or regional enteritis is an inflammatory bowel disease that involves the small intestine and causes abdominal pain, diarrhea and bleeding.
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The microbes reappear years later and can cause serious health problems such as seen in tuberculosis cases. Current testing methods to find these hidden microbes exist, but require a long time to complete and often delay effective treatment for weeks or even months.
UCF Associate Professor J. Manuel Perez and Professor Saleh Naser and their research team have developed a method using nanoparticles coated with DNA markers specific to the elusive pathogens. The technique is effective and more accurate than current methods at picking up even small amounts of a pathogen. More important, it takes hours instead of weeks or months to deliver results, potentially giving doctors a quicker tool to help patients.
![The Splendid Stomach - Animation]( "The Splendid Stomach - Animation")
Stomach is the organ where food is mixed, stored and partially digested.
"Our new technique has surpassed traditional molecular and microbiological methods," said Naser, a professor at the UCF College of Medicine. "Without compromising specificity or sensitivity, the nano-method produced reliable and accurate results within hours compared to months."
The group's translational research works is published in today's edition of the journal PLOS One.
Source: Eurekalert
The Splendid Stomach - Animation
Stomach is the organ where food is mixed, stored and partially digested.
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"Our new technique has surpassed traditional molecular and microbiological methods," said Naser, a professor at the UCF College of Medicine. "Without compromising specificity or sensitivity, the nano-method produced reliable and accurate results within hours compared to months."
The group's translational research works is published in today's edition of the journal PLOS One.
Source: Eurekalert
Nanotechnology To Reduce Rejection Of Implants
Nanotechnology can come in handy to reduce rejection of implants like or hip replacements or pacemakers, say researchers at the University of Gothenburg.
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