A mother's care can impact the baby's body clock and health after birth, reveals a new study. Lifestyle related diseases like heart disease and obesity can be avoided by reducing abnormalities in the body clock of offspring. The study was published in The Journal of Physiology.
The body has an internal clock that regulates sleepiness over a 24 hour period, called your circadian rhythm. The circadian system is important so that processes in our body are synchronised with day and night, i.e. when it is light or dark outside. Disturbances in these mechanisms can lead to poor health, such as heart disease.
Circadian Rhythm Sleep Disorders
Circadian rhythm (also known as sleep/wake cycle or the body clock) is a biological process that follows an internal cycle of roughly 24 hours.
Advertisement
‘A mother can impact the body clock and health of offspring after birth, according to new research published in The Journal of Physiology.’
Tweet it Now
The mother-offspring interaction is very important for health later in adulthood. This is the first study to provide compelling evidence that the circadian characteristics of a mother may positively affect the likelihood of disease developing in offspring. Providing better maternal care significantly reduced abnormalities in the circadian system and resulted in a lower likelihood of development of heart disease.
The study conducted by the Institute of Physiology of the Czech Academy of Sciences was performed in two strains of laboratory rats, in which the maternal care and synchrony of their circadian clocks with external day/night cycle differed.
![Our Body Clock Affects Severity of Autoimmune Disease]( "Our Body Clock Affects Severity of Autoimmune Disease")
Maintaining a good body clock is believed to lead to good health for humans, and disrupting the circadian rhythm has been associated with immune diseases.
The effect of maternal care provided by the genetic mother of these pups was compared with maternal care of the foster mother. The pups either had an aberrant circadian system and were genetically determined to develop disease in adulthood or they were healthy controls.
The researchers tested the effect of maternal care on the body clock before and just after weaning, and on their activity rhythms, heart rate and blood pressure in adulthood. Proper maternal care provided to pups genetically predisposed to develop disease led to improvement of their clock function and abolished the rise in their heart rate in adulthood.
The data obtained in pups before weaning were based on population samples because the researchers could not assess circadian rhythms of the clocks in each individual pup within the body without disturbing the maternal behaviour. Additionally, in the rat strain spontaneously developing disease, the molecular mechanisms connecting the circadian clock and the pathology has not been understood.
Alena Sumova, corresponding author for the study said: "These results point to a real possibility to reduce abnormalities in the offspring's body clock and therefore limit the progression of disease in order to improve health. Our future research will be directed at understanding in more detail how an aberrant circadian system contributes to the progression of disease. We believe that this research is worth future explorations as it may provide novel therapies for serious life-style related diseases in humans.'
Source: Eurekalert
Our Body Clock Affects Severity of Autoimmune Disease
Maintaining a good body clock is believed to lead to good health for humans, and disrupting the circadian rhythm has been associated with immune diseases.
Advertisement
The effect of maternal care provided by the genetic mother of these pups was compared with maternal care of the foster mother. The pups either had an aberrant circadian system and were genetically determined to develop disease in adulthood or they were healthy controls.
The researchers tested the effect of maternal care on the body clock before and just after weaning, and on their activity rhythms, heart rate and blood pressure in adulthood. Proper maternal care provided to pups genetically predisposed to develop disease led to improvement of their clock function and abolished the rise in their heart rate in adulthood.
The data obtained in pups before weaning were based on population samples because the researchers could not assess circadian rhythms of the clocks in each individual pup within the body without disturbing the maternal behaviour. Additionally, in the rat strain spontaneously developing disease, the molecular mechanisms connecting the circadian clock and the pathology has not been understood.
Alena Sumova, corresponding author for the study said: "These results point to a real possibility to reduce abnormalities in the offspring's body clock and therefore limit the progression of disease in order to improve health. Our future research will be directed at understanding in more detail how an aberrant circadian system contributes to the progression of disease. We believe that this research is worth future explorations as it may provide novel therapies for serious life-style related diseases in humans.'
Source: Eurekalert
Genes Responsible for Regulating Body Clock Discovered
Internal body clock is wired in your genes, revealed study. Circadian regulation may be directly connected to cellular stress.
Advertisement
 Circadian Rhythm Boosts Body's Response to Intestinal InfectionsCircadian rhythms boost the body's ability to fight intestinal bacterial infections. Targeted therapy that alters circadian gene controlled system response may turn into reality. | Advertisement
|
Advertisement
Recommended Readings
Latest Child Health News
Side-effects of valproate drug taken during pregnancy, enhance the expression of Rnf146 gene, causing autism spectrum disorder in fetus.
Children with amblyopia or lazy eye who underwent digital vision training, showed no appreciable improvement in their eyesight.
In 2022, over 20% of children worldwide lacked adequate calories for growth, with 45+ million showing wasting (underweight for height).
After PCV7 licensure, pneumococcal infection rates in children aged 5+ with sickle cell disease significantly decreased.
Breast milk concentration of certain key proteins indicates abundance of healthy bacteria in babies' guts.
