About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Maternal Obesity May Up Childhood Cancer

by Mary Selvaraj on July 11, 2019 at 3:51 PM
Font : A-A+

Maternal Obesity May Up Childhood Cancer

Maternal obesity is associated with higher risk of childhood cancer. Mother's size is one of the factors that independently contribute to child's risk for cancer.

A new study from the University of Pittsburgh Graduate School of Public Health and UPMC Hillman Cancer Center found that children born to obese mothers were more likely to develop cancer in early childhood.

Advertisement


Using Pennsylvania birth records, the researchers found a correlation between pre-pregnancy body-mass index (BMI) in mothers and subsequent cancer diagnosis in their offspring, even after correcting for known risk factors, such as newborn size and maternal age. The final version of the paper published online today in the American Journal of Epidemiology

"Right now, we don't know of many avoidable risk factors for childhood cancer," said lead author Shaina Stacy, Ph.D., postdoctoral scholar in the Pitt Public Health Department of Epidemiology and UPMC Hillman Cancer Center. "My hope is that this study can be, in a way, empowering and also motivating for weight loss."
Advertisement

Stacy and colleagues pored through nearly 2 million birth records and about 3,000 cancer registry records filed in the state of Pennsylvania between 2003 and 2016 and found that children born to severely obese mothers--BMI above 40--had a 57% higher risk of developing leukemia before age 5. Weight and height also were individually associated with increased leukemia risk.

Further analysis showed that it wasn't simply that larger women were giving birth to larger babies or that heavier women tended to be older--known risk factors for childhood cancer--but rather, a mother's size independently contributed to her child's risk.

The researchers think the root cause of the effect they're seeing has something to do with insulin levels in the mother's body during fetal development, or possibly changes to the mother's DNA expression that are passed to her offspring.

Importantly, not all levels of obesity carry the same risk. Among the obese women in the study, higher BMI came with higher cancer rates in their children. So, even small amounts of weight loss can translate to a real reduction in risk, Stacy said.

"We are dealing with an obesity epidemic in this country," said senior author Jian-Min Yuan, M.D., Ph.D., professor of epidemiology at Pitt Public Health and co-leader of the cancer epidemiology and prevention program at UPMC Hillman Cancer Center. "From a prevention point-of-view, maintaining a healthy weight is not only good for the mother, but also for the children, too."



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Monkeypox Outbreak: What it is, How Does it Spread & the Prevention
Seasonal Allergy Medications
How to Choose the Best Eczema-Friendly Moisturizer for Children?
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Bariatric Surgery Obesity Cancer and Homeopathy Bulimia Nervosa Acute Lymphoblastic Leukemia Body Mass Index Cancer Facts Liposuction Cancer Tattoos A Body Art 

Most Popular on Medindia

How to Reduce School Bag Weight - Simple Tips Hearing Loss Calculator Calculate Ideal Weight for Infants Sanatogen Drug - Food Interactions Loram (2 mg) (Lorazepam) Selfie Addiction Calculator Turmeric Powder - Health Benefits, Uses & Side Effects Diaphragmatic Hernia Sinopril (2mg) (Lacidipine)

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use