About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Lymphadenectomy Improves Survival for Patients With Node-Positive Gastric Cancer

by VR Sreeraman on August 29, 2009 at 4:01 PM
Font : A-A+

 Lymphadenectomy Improves Survival for Patients With Node-Positive Gastric Cancer

Many studies favor an extended lymphadenectomy at the time of a potentially curative gastrectomy for node-positive gastric cancer, and the risk of long-term death tends to decrease when the number of resected lymph nodes increases to about 25.

However, few studies have assessed the relative contribution of the total number of resected lymph nodes to the outcome of patients with node-negative gastric cancer. Further studies are needed to know how the numbers of dissected LNs may affect the survival outcome of patients with node-negative gastric cancer.

Advertisement

A research article to be published on August 21, 2009 in the World Journal of Gastroenterology addresses this question. This study was performed by a team led by Professor Chang-Ming Huang from Department of Oncology, Affiliated Union Hospital of Fujian Medical University.

Two hundred and eleven patients with node-negative gastric cancer who underwent D2 curative resection were analyzed retrospectively. This article went ahead to investigate the effect of the number of lymph nodes resected in a large population of patients with node-negative gastric cancer. The number of dissected LNs emerges as one of the most important prognostic indicators.
Advertisement

Patients with comparable depth of invasion had a better survival as the number of resected LNs increased. The patients had better long-term survival outcomes with LN counts of > 15 for pT1-2, > 20 for pT3-4, and > 15 for the entire cohort. There was a statistically significant, negative correlation between the number of resected LNs and the recurrence rate.

The study also found that the number of dissected LNs was not significantly correlated with the post-operative complication rate.Based on their results, the authors suggest that a large number of dissected lymph nodes in the procedure of D2 dissection is recommended, in order to improve the long-term survival and reduce the recurrence rate of patients with node-negative gastric cancer.

Suitable increments of the number of dissected LNs would not increase the post-operative complication rate. Therefore, this is an interesting and well-done study investigating the long-term effect of the number of resected lymph nodes on the prognosis of patients with node-negative gastric cancer.

Source: Eurekalert
SRM
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Test your Knowledge on Heart Transplantation
Test Your Knowledge on Lung Transplantation
Baldness can be Cured and Prevented: let us see How!
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Gastric Cancer Cancer and Homeopathy Cancer Facts Cancer Tattoos A Body Art 

Most Popular on Medindia

Blood - Sugar Chart Drug Side Effects Calculator The Essence of Yoga Pregnancy Confirmation Calculator Vent Forte (Theophylline) Turmeric Powder - Health Benefits, Uses & Side Effects Sanatogen Drug Interaction Checker Color Blindness Calculator Daily Calorie Requirements
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use