About My Health Careers Internship MedBlogs Contact us

“Low-Yield” Cigarettes High On Slashing Human Reproduction Rates

by Tanya Thomas on December 10, 2008 at 9:42 AM
Font : A-A+

“Low-Yield” Cigarettes High On Slashing Human Reproduction Rates

A new study has warned smokers that the so-called "harm-reduction" cigarettes may not be harm-reducing at all. In fact, they might be worse than the traditional, high-nicotine alternatives when it comes to toxicity.

Researchers from University of California - Riverside have found that smoke from the "light" or "low-yield" harm-reduction cigarettes retains toxicity, and that this can have an adverse impact on prenatal development.


"Many chemicals found in harm-reduction cigarette smoke have not been tested, and some are listed by manufacturers as safe," said lead researcher Prue Talbot and a professor of cell biology.

"But our tests on mice clearly show that these chemicals adversely affect reproduction and associated development processes.

"The effects are likely to be the same in humans, in which case pregnant women would be particularly vulnerable to the effect of smoke from these cigarettes," she added.

During the study, the researchers used mouse embryonic stem cells (mESCs) as a model for pre-implantation embryos-embryos that have not yet implanted in the wall of the uterus-and compared the toxicity on these cells of cigarette smoke emanating from traditional and harm-reduction brands.

They analyzed the effects of two kinds of cigarette smoke: mainstream smoke, which is smoke actively inhaled by smokers; and sidestream smoke, which is smoke that burns off the end of a cigarette.

The results showed that both kinds of smoke from traditional and harm-reduction cigarettes were toxic to pre-implantation embryos and could retard growth or kill embryonic cells at the stage of development.

Moreover, mainstream smoke and sidestream smoke from harm-reduction cigarettes were found to be more potent than the corresponding smoke from traditional brands of cigarettes.

"This result was unexpected since harm reduction brands purportedly have lower concentrations of toxicants," Talbot said.

"Clearly, the tobacco companies have not eliminated all toxins from harm-reduction brands of cigarettes," said Talbot, who also is the director of the UCR Stem Cell Center.

"We found that both mainstream and sidestream smoke from traditional and harm-reduction cigarettes hindered the attachment of mESCs to extracellular materials.

"Such attachment is crucial to normal embryonic development. Moreover, cell survival and proliferation-also necessary for embryonic growth-were hindered as well.

"This may be because sidestream smoke is produced at a lower temperature and therefore contains higher concentrations of toxicants," Talbot added.

The study appears in the journal Human Reproduction.

Source: ANI

News A-Z
News Category
What's New on Medindia
Memory Loss - Can it be Recovered?
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Health Hazards of Smoking Smoking And Cancer Smoking among Women Cigarette Smoking - A Silent Killer Antioxidants to Help You When You Quit Smoking 

Recommended Reading
Health Hazards of Smoking
Smoking causes many diseases and affects the overall health of smokers....
Smoking Risk Calculator
Do you smoke cigarettes daily? Use medindia smoking risk calculator and calculate your reduced Life ...
Antioxidants to Help You When You Quit Smoking
Smoking is injurious to health, but it sure is a tough addiction to stop. Cure yourself with the pow...
Cigarette Smoking - A Silent Killer
Smoking kills the smoker silently, pushing him towards serious illnesses, which slowly lead to ......
Smoking among Women
Tobacco use in women is on the rise. The health risks of tobacco are far too many has never done a w...
Smoking And Cancer
Smoking is the most important preventable cause of cancer in the world....

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use