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Iron Loading can Cause Ataxia

by Rajashri on Sep 11 2009 12:20 AM

University of Sydney (U-S) researchers have found in a mice study that debilitating hereditary disease like Friedreich’s Ataxia (FA) can be caused by iron build-up in cellular mitochondria.

FA is linked to brain and cardiac disorders and is a fatal disease usually ending in early death. “The terrible part is that these children grow up knowing the joys of self-sufficiency, being able to walk and function normally before they are struck down,” said author Des Richardson.

Michael Huang, study co-author said, “It’s great to work on such an intractable disease and by unveiling its underlying nuts and bolts to get results that can potentially help lots of people.”

The details of the study appear in The Proceedings of the National Academy of Science.


Source-Medindia
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