Insulin Pills for Diabetics on the Anvil

Insulin pills that could make it easier for patients to manage diabetes are finally moving ahead in clinical trials.

The new development may soon make painful insulin jabs a thing of the past.

Diabetes Essentials: Types, Complications, Management & Treatment
Diabetes is a metabolic disease caused by insulin deficiency that leads to high blood sugar levels and several associated complications if left untreated.

The topic has been highlighted in the current issue of Chemical and Engineering News (C and EN), ACS' weekly newsmagazine.

C and EN Senior Correspondent Ann Thayer notes that drug manufacturers have tried for years to develop oral insulin without much success.

Insulin is a peptide hormone that people with diabetes currently take by injection to bring their blood sugar to within normal levels.

Diabetes and Exercise
Regular exercise especially in type II diabetes not only helps reduce the sugar but also reduces the demand for medication by 20% and helps you stay healthy.

But doing so requires uncomfortable, inconvenient injections that can make patients reluctant to use the drug frequently enough to adequately control their blood sugar. An oral form of insulin could help solve this problem.

However, stomach acids and enzymes easily destroy insulin and other protein-based drugs. Scientists have had difficulty finding an effective way to eliminate this problem.

Diabetic Diet - Diabetes Mellitus
The diabetic diet most often recommended is high in dietary fiber (especially soluble fiber) and nutrients, but low in fat (especially saturated fat) and moderate in calories.

They've responded to this challenge by developing special coatings for insulin pills that prevent stomach acid from destroying them.

Scientists also are using additives that make it easier for the intestine to absorb large molecules like insulin.

Gestational Diabetes About
The condition is not caused by a lack of insulin, but by the action of hormones produced during pregnancy that blocks the action of insulin.

After years of setbacks, signs of success may be at hand. Several insulin pills are now in various stages of clinical trials, and proof of concept may allow them to move into late-stage and more rigorous clinical testing.

However, only time will tell whether these much-anticipated pills will make it to the market.

Source-ANI