About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Increasing the Number of Kidney Transplants

by VR Sreeraman on August 23, 2009 at 11:18 AM
Font : A-A+

 Increasing the Number of Kidney Transplants

In most transplant centers, the kidneys of very young deceased donors are transplanted together into one patient. According to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), a single kidney from a very young deceased donor maintains the health of an adult with kidney failure.

Determining the minimum donor age or body weight for splitting kidneys for transplant is controversial. Transplanting both pediatric kidneys into an adult theoretically provides better kidney function, and surgeons do not usually divide kidneys when the donor is under five years of age. However, giving each of two patients in need one organ from the same donor could increase kidney transplants: in the United States approximately 80,000 individuals are waiting for kidney transplants, and 4,000 die each year before receiving transplants. Rubin Zhang, MD (Tulane Abdominal Transplant Institute), and his colleagues compared the long-term health of adult patients after they were transplanted with either single pediatric kidneys from donors less than five years of age or single kidneys from donors more than five but less than 10 years of age.

Advertisement

The researchers' study included all 79 adults who were transplanted at the Tulane Abdominal Transplant Institute with single pediatric kidneys from deceased donors aged 10 years or less between January 1996 and June 2007. Physicians transplanted a single pediatric kidney if it was healthy enough for splitting and the recipient consented. Half of the adults received single pediatric kidneys from donors less than five years of age. The other half received single kidneys from donors aged five to 10 years.

While more patients in the group that received a kidney from the youngest donors (73%) needed ureteral stents (tubes inserted to help drain urine from the kidney) than patients in the other group (38%), complications that required additional surgery were similar in the two groups. Patients in the two groups experienced similar rates of kidney rejection and delayed kidney function.
Advertisement

In both groups, kidney function improved dramatically in the first year after transplant, and it continued to improve into the third year. Furthermore, patients in the two groups lived a similar length of time. The youngest donor in the study was a nine-month old female; both of her donated kidneys remain healthy more than six years post-transplantation into two different recipients.

While other studies have reported more complications when single kidneys from very young donors are transplanted into adults, this study found that the practice is safe and effective. "Single pediatric kidney transplants from donors less than five years can be utilized with acceptable complications and good long-term outcomes" the authors concluded.

Source: Eurekalert
SRM
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Test Your Knowledge About Chromosomes?
Eating During Sunlight Hours Minimizes Mood Vulnerabilities
Know More About the Digestive System
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Urinary Stones In Children Vesico-Ureteric Reflux Causing UTI in Children Hydronephrosis / Antenatal Counseling Kidney Disease Kidney Kidney Health Stones in Urinary Tract Renal Tubular Acidosis Kidney Biopsy Prevention of Kidney Disease 

Most Popular on Medindia

Drug Side Effects Calculator Turmeric Powder - Health Benefits, Uses & Side Effects Vent Forte (Theophylline) Iron Intake Calculator Noscaphene (Noscapine) Accident and Trauma Care Post-Nasal Drip A-Z Drug Brands in India Pregnancy Confirmation Calculator Sanatogen
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Increasing the Number of Kidney Transplants Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests