About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Increased Aneurysms Risk in Men Investigated in New Brit Study

by Tanya Thomas on June 21, 2010 at 10:41 AM
Font : A-A+

 Increased Aneurysms Risk in Men Investigated in New Brit Study

A new research, currently underway at the University of Leicester UK, is out to identify reasons behind the increased risk of Abdominal Aortic Aneurysms (AAA) in men.

In her doctoral study, Cardiovascular Sciences student Lisa Bloomer is looking into the causes of the male predominance of AAA, with a particular emphasis on genetic basis of the disease.

Advertisement

loomer said: "AAA is the ballooning of the abdominal part of the major artery in the body. Rupturing of the weakened artery causes death in 80% of cases due to massive blood loss. The Y chromosome, which is present exclusively in men, may hold the key to deciphering why AAA has a 50% higher diagnosis rate in men than women.

"Staggeringly, AAA kills 10,000 men each year in England and Wales alone. The male-specific Y chromosome is a prime genetic suspect in AAA development, possibly acting as an independent risk factor."
Advertisement

A thorough DNA analysis tracking the most common forms of the Y chromosome amongst British men with AAA and those who are free of the disease is to be undertaken.

It is hoped that the results from this research will be able to identify those individuals with a higher risk of developing AAA due to their Y chromosome.

Bloomer said: "We anticipate that certain forms of the Y chromosome will be more common in those with AAA than across the general population. Elucidation of a specific form of Y chromosome which significantly increases the risk of AAA development in men could potentially save thousands of lives each year."

Bloomer's doctoral supervisor, Dr Maciej Tomazewski, Senior Lecturer in Cardiovascular Medicine, said: "The major portion of the Y chromosome, the male specific region, is inherited intact from fathers to sons. Tracking the paternal lineages of this region has proved to be successful in our previous studies on coronary artery disease. Lisa's project is the first investigation that is using this strategy in relation to AAA."

Preliminary results from the research will be showcased at the University of Leicester's Festival of Postgraduate Research on June 24.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
World Heart Day in 2022- Use Heart for Every Heart
Anemia among Indian Women and Children Remains a Cause of Concern- National Family Health Survey-5
H1N1 Influenza Prevention in Children: What Parents Need to Know
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Aneurysm Abdominal Aortic Aneurysm 

Most Popular on Medindia

Calculate Ideal Weight for Infants Blood - Sugar Chart Drug Side Effects Calculator Noscaphene (Noscapine) Color Blindness Calculator Loram (2 mg) (Lorazepam) Pregnancy Confirmation Calculator Blood Pressure Calculator The Essence of Yoga A-Z Drug Brands in India
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Increased Aneurysms Risk in Men Investigated in New Brit Study Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests