About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

How to Tackle Dengue? by Converting Female Mosquitoes into Harmless Males

by Bidita Debnath on May 25, 2015 at 12:15 AM
Font : A-A+

How to Tackle Dengue? by Converting Female Mosquitoes into Harmless Males

Only female mosquitoes bite because they need blood for developing eggs, and researchers believe that a higher ratio of males could reduce disease transmission.

That, in fact, provides a foundation for developing mosquito control strategies by converting females into harmless males or selectively eliminating deadly females, they say.

Advertisement

Researchers have now identified a gene that is responsible for sex determination in mosquitoes and that can transmit yellow fever, dengue and chikungunya viruses.

"The gene called 'Nix' provides us with exciting opportunities to harness mosquito sex in the fight against infectious diseases because maleness is the ultimate disease-refractory trait," said Zhijian Jake Tu, professor of biochemistry at the Virginia Polytechnic Institute and State University (Virginia Tech).
Advertisement

The scientists injected "Nix" into mosquito embryos and found more than two-thirds of the female mosquitoes developed male genitals and testes.

When they removed "Nix" using a genome-editing method, male mosquitoes developed female genitals.

"We are not there yet but the ultimate goal is to be able to establish transgenic lines that express Nix in genetic females to convert them to harmless males," said Zach Adelman, associate professor of entomology and co-author.

Aedes aegypti is among the small fraction of mosquito species that transmit pathogens to humans.

"Targeted reduction of Aedes aegypti populations in areas where they are non-native could have little environmental impact, and drastically improve human health," noted Brantley Hall, co-first author on the paper.

The study appeared in the journal Science Express.

Source: IANS
Advertisement
Advertisement
Advertisement
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

How to Tackle Dengue? by Converting Female Mosquitoes into Harmless Males Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests