About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Higher Risk for Early Dementia Linked To Mild Cognitive Impairment at Parkinson's Disease Diagnosis

by Rukmani Krishna on March 27, 2013 at 10:46 PM
Font : A-A+

Higher Risk for Early Dementia Linked To Mild Cognitive Impairment at Parkinson's Disease Diagnosis

According to a report, mild cognitive impairment at the time of Parkinson's disease (PD) diagnosis appears to be associated with an increased risk for early dementia in a Norwegian study. The report was published Online First by JAMA Neurology, a JAMA Network publication.

Patients with PD have an increased risk for dementia (PDD) compared with healthy individuals and researchers sought to examine the course of mild cognitive impairment (MCI) and its progression to dementia in a group of patients with PD. The Norwegian ParkWest study is an ongoing population-based study of the incidence, neurobiology and prognosis of PD in western and southern Norway, according to the study background.

Advertisement

The study by Kenn Freddy Pedersen, M.D., Ph.D., of Stavanger University Hospital, Norway, included 182 patients with PD monitored for three years. More patients with MCI than without MCI at baseline (10 of 37 [27 percent] vs. 1 of 145 [0.7 percent]) progressed to dementia during follow-up. Of those with MCI at baseline, 8 of 37 (21.6 percent) had MCI that reverted to normal cognition during follow-up, according to the study results.

The results also show that mild cognitive impairment at the one-year visit was associated with a similar progression rate to dementia (10 of 36 patients [27.8 percent] and reversion rate to normal cognition (7 of 36 [19.4 percent]). Of the 22 patients with persistent MCI at baseline and the one-year visit, 10 (45.5 percent) developed dementia and only two (9.1 percent) had MCI that reverted to normal cognition by the end of the study.
Advertisement

"This prospective population-based study of an incident PD cohort demonstrates that MCI within the first year of PD diagnosis signals a highly increased risk for early incident dementia. More than 25 percent of patients with MCI at diagnosis of PD developed dementia within three years of follow-up compared with less than 1 percent of patients without MCI at PD diagnosis. Among patients with MCI at baseline and one year of follow-up, almost half progressed to dementia. These findings support the validity of the MCI concept in patients with early PD," the study authors conclude.

Source: Newswise
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
Toothache
World AIDS Day 2021 - End Inequalities, End AIDS
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Alzheimers Disease Dementia Vascular Dementia Stroop Effect 

Recommended Reading
Drug Firm to Pay Huge Damages to Parkinsons Disease Sufferer
A French Parkinson's sufferer who turned into a gambler and thief, with compulsive homosexual urges ...
Robot Controlled by Cables may Help in Stroke and Parkinsonís Patients
A unique robotic device has been developed by experts at Florida Atlantic University. This robot ......
Alzheimers Disease
Alzheimer's disease is a progressive neurodegenerative disease affecting memory and thinking and mak...
Dementia
Dementia has become a very big concern as we have an aging population across the world. Dementia is ...
Stroop Effect
Stroop Effect causes a delay in reaction time with incongruent stimuli and the applications of the ....
Vascular Dementia
Vascular dementia is the second most common form of dementia. Though it has no cure, you can still l...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use