New study in The FASEB Journal identifies uterine bitter taste receptors as potential deterrents to premature labor.

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Going into preterm labor does not mean you'll have a premature baby. Up to half of the women who experience preterm labor eventually deliver at 37 weeks or later.
Zhuge and colleagues attached strips of human and mouse uterine myometrium tissue (also known as smooth muscle) to a machine that measured their contraction efforts. The researchers first exposed the tissue to native hormones such as oxytocin and chemical compounds to make it contract, mimicking normal or premature labor. They then exposed the tissue to bitter substances.
By activating the bitter taste receptors in the uterus, the bitter substances relaxed the contracted uterine muscle tissue more completely than the current drugs used to prevent preterm labor in humans. The researchers also found that giving mice bitter substances before they showed any premature contractions prevented them from having early deliveries.
Source-Eurekalert
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