Medindia
Advertisement

Epilepsy Drugs During Pregnancy Linked to Birth Defects


Highlights
  • Epilepsy occurs due to the malfunction of neurons in the brain.
  • Anti-epileptic medications are used to treat seizures.
  • Carbamazepine, topiramate, phenytoin are linked to birth defects in children.

Epilepsy Drugs During Pregnancy Linked to Birth Defects
Birth defects were linked with the use of certain type of epileptic medications, finds a study from the Universities of Liverpool and Manchester.

Epilepsy is a neurological condition which is represented by seizures. It is caused due to the malfunctioning of neurons in the brain. Epileptic women are advised to follow medications even during pregnancy. These medicines might result in a high risk of malformation or birth defect to the baby.
Advertisement


The research study aimed to find the risk of birth defects in children if the women had taken antiepileptic drugs during pregnancy.

The study findings were published in Cochrane Database of Systematic Reviews.

Around 50 published studies were analyzed, and the use of sodium valproate drug during pregnancy was found to have a 10% chance of birth defects in the child.
Advertisement

Study Findings

Drugs like carbamazepine, topiramate or phenytoin, when taken during pregnancy, were found to show an increased risk of birth defects in children.

Skeletal and limb defects, cardiac defects, craniofacial defects and neural defects are some of the different types of birth defects in children.

Phenobarbital drug was found to be associated with an increased risk of cardiac defects in children.

Newer epileptic drugs like levetiracetam, lamotrigine decreased the risk of birth defects when compared to epileptic medications like carbamazepine, topiramate or phenytoin.

Tony Marson, Professor of Neurology, University of Liverpool's Institute of Translational Medicine, said: "This is a really important review that informs complex discussions during consultations about epilepsy treatment choices for women of childbearing potential, who represent around a third of people with epilepsy worldwide.

"Based on current evidence, levetiracetam and lamotrigine appear to be the AEDs associated with the lowest level of risk, but more data are needed, particularly concerning individual types of malformation.



Source: Medindia
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
Stroop Effect
Plant-Based Diet may Reduce the Risk of COVID-19
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Club Foot Drug Toxicity Epilepsy Birth Defect - Genetic Birth Defects Drug-Induced Birth Defects Environmental Birth Defects Birth defects - Infections Multifactorial Birth Defects Birth Defect - Structural Defects 

Recommended Reading
Newer Epileptic Drugs in Pregnant Women Not Associated With Lower IQ Levels in Children
Newer epileptic drugs like topiramate and levetiracetam during pregnancy were not associated with .....
Epilepsy During Pregnancy
Seizures or epilepsy during pregnancy can be fatal for both the mother and child and needs urgent .....
Treatment for Fits | Epilepsy | Convulsions
Epilepsy treatment basically involves addressing the underlying cause and avoiding the triggering .....
Birth Defect - Genetic
Achondroplasia is a genetic disorder which is one of the leading causes of dwarfism ...
Birth Defect - Structural Defects
A structural birth defect means that a specific body part is missing or mal-formed during the embryo...
Birth Defects
Birth defects are abnormalities that occur in babies which affect how the body looks, works or both....
Birth Defects - Infections
Birth defects are abnormalities, which occur before the birth of the baby and can be caused due to g...
Club Foot
Clubfoot is a congenital foot deformity affecting the shape or position of one or both feet. Around ...
Drug Toxicity
Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a d...
Drug-Induced Birth Defects
Birth defects are abnormalities of function, structure or metabolism that are present since birth. T...
Environmental Birth Defects
Birth defects caused due to environmental teratogens like drugs, microorganisms or exposure to radia...
Epilepsy
Fits or convulsions or Epilepsy is characterized by recurrent, involuntary seizures and is described...
Multifactorial Birth Defects
Encyclopedia section of medindia gives in brief General Info about About Multifactorial Birth ......

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use