The 'gut instinct' may have an impact on how we react to fear, researchers believe.
By cutting the afferent nerve fibres in rats, a team of scientists led by Urs Meyer, a researcher in the group of ETH Zurich professor Wolfgang Langhans, turned this two-way communication into a one-way street, enabling the researchers to get to the bottom of the role played by gut instinct.
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In the test animals, the brain was still able to control processes in the abdomen, but no longer received any signals from the other direction.
In the behavioural studies, the researchers determined that the rats were less wary of open spaces and bright lights compared with controlled rats with an intact vagus nerve. "The innate response to fear appears to be influenced significantly by signals sent from the stomach to the brain," says Meyer.
![New Approach for Sampling Gut Bacteria Developed]( "New Approach for Sampling Gut Bacteria Developed")
Massachusetts General Hospital and the Harvard School of Public Health scientists have discovered a new protocol for collecting saliva and stool samples for genomic and transcriptomic analyses.
Nevertheless, the loss of their gut instinct did not make the rats completely fearless: the situation for learned fear behaviour looked different. In a conditioning experiment, the rats learned to link a neutral acoustic stimulus - a sound - to an unpleasant experience. Here, the signal path between the stomach and brain appeared to play no role, with the test animals learning the association as well as the control animals.
If, however, the researchers switched from a negative to a neutral stimulus, the rats without gut instinct required significantly longer to associate the sound with the new, neutral situation. This also fits with the results of a recently published study conducted by other researchers, which found that stimulation of the vagus nerve facilitates relearning, says Meyer.(ANI)
Source: ANI
New Approach for Sampling Gut Bacteria Developed
Massachusetts General Hospital and the Harvard School of Public Health scientists have discovered a new protocol for collecting saliva and stool samples for genomic and transcriptomic analyses.
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Nevertheless, the loss of their gut instinct did not make the rats completely fearless: the situation for learned fear behaviour looked different. In a conditioning experiment, the rats learned to link a neutral acoustic stimulus - a sound - to an unpleasant experience. Here, the signal path between the stomach and brain appeared to play no role, with the test animals learning the association as well as the control animals.
If, however, the researchers switched from a negative to a neutral stimulus, the rats without gut instinct required significantly longer to associate the sound with the new, neutral situation. This also fits with the results of a recently published study conducted by other researchers, which found that stimulation of the vagus nerve facilitates relearning, says Meyer.(ANI)
Source: ANI
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