The study has found that EGCG, the active biologic constituent in green tea, changed the metabolism of pancreatic cancer cells by suppressing the expression of an enzyme associated with cancer, LDHA.
Researchers also found that an enzyme inhibitor, oxamate, which is known to reduce LDHA activity, also disrupted the pancreatic cancer cells metabolic system.
Wai-Nang Lee, MD, said that it was earlier believed that molecular mechanism is required in order to treat cancer but this study stated that they can change the metabolic system and have an impact on cancer.
This new knowledge will open the door to a whole new area of cancer research and could allow trying altering the course of cancer or preventing cancer with the help of different foods, he added.
The study was published online in the journal Metabolomics.