Medindia
Advertisement

Four New Genes Added for Upping Familial Breast Cancer Risk

by Bidita Debnath on June 6, 2014 at 12:13 AM
Font : A-A+

 Four New Genes Added for Upping Familial Breast Cancer Risk

Scientists have added 4 new genes to the growing list of those known to cause increased breast cancer risk when mutated.

Sean Tavtigian, Ph.D., an HCI investigator, professor in the Department of Oncological Sciences at the University of Utah (U of U), and one of three joint-principal investigators on the study, said BRCA1 and BRCA2 aren't the whole story when it comes to inherited breast cancer risk. We've known for a long time that more genes had to be responsible and several have since been discovered, by us and by others.

Advertisement

Tavtigian said originally, the gene we are currently studying, called RINT1, was not considered a human cancer susceptibility gene. But then we discovered there was a two- to three-fold increase in risk for breast cancer in families that carry a mutation in that gene.

Surprisingly, RINT1 was also found to increase risk for a broad spectrum of gastrointestinal and gynecological cancers in these families.

In another study led by Tavtigian, mutations in three other genes-MRE11A, RAD50, and NBN-were also confirmed to increase breast cancer risk, as reported in the journal Breast Cancer Research June 3.

The findings have been published in the journal Cancer Discovery.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Sedentary Behavior Precipitates Night-Time Hot Flashes
Gonorrhea
World Alzheimer's Day 2021 - 'Know Dementia, Know Alzheimer's
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Women and Cancer Breast Biopsy Pagets disease of the breast Mastitis Cancer and Homeopathy Breast Cancer Facts Cancer Facts Cancer Tattoos A Body Art Breasts - Structures and Types 

Recommended Reading
Study Identifies New Test to Predict If Breast Cancer Will Spread
A new test to predict if breast cancer will spread in a particular case has been identified in a ......
Promising Results With New Drug to Prevent Breast Cancer
Preventing a return of breast cancer in young women is more effective with a new treatment option .....
Increased Lung Risk With Breast Cancer Gene
A smoker's risk of developing lung cancer increases doubly in the presence of a notorious breast ......
Researchers Find Goserelin Beneficial in Preserving Fertility of Young Women Undergoing Chemo for Breast Cancer
Goserelin can help preserve the fertility of young women who are undergoing chemotherapy for ......
Breast Biopsy
Breast biopsy involves removing a sample of breast tissue to determine whether it is cancerous or .....
Breasts - Structures and Types
Different stages of breast development in women and an in-depth look at the breast/bust and its ......
Mastitis
Mastitis is a common cause of tenderness, swelling and pain in breast, owing to inflammation in the ...
Pagets disease of the breast
A detailed description of the Paget's disease of the breast, characteristic signs and symptoms, dete...
Tattoos A Body Art
Tattoos are a rage among college students who sport it for the ‘cool dude’ or ‘cool babe’ look...
Women and Cancer
Cancer is one of the frequently talked about and most feared disease that falls under the genre of l...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use