About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Researchers Find Goserelin Beneficial in Preserving Fertility of Young Women Undergoing Chemo for Breast Cancer

by Kathy Jones on May 31, 2014 at 4:41 PM
Font : A-A+

 Researchers Find Goserelin Beneficial in Preserving Fertility of Young Women Undergoing Chemo for Breast Cancer

Goserelin can help preserve the fertility of young women who are undergoing chemotherapy for certain types of breast cancer, a new study reveals.

The cancer drug also appeared to improve survival, according to the results of a phase III clinical trial unveiled at the American Society for Clinical Oncology annual meeting.

Advertisement

Early menopause can be triggered by breast cancer chemotherapy. Some women resume menstruating after chemo and can have children, but many cannot.

"I think these findings are going to change our clinical practice," said senior study author Kathy Albain of Loyola University Medical Center.

Some 49,000 women under 50 are diagnosed with breast cancer each year in the United States, making up about a quarter of all breast cancer cases.
Advertisement

About 15 percent of young women have cancers that are hormone receptor negative, and these are the women who could benefit from taking goserelin to essentially put the ovaries at rest during chemo, researchers said.

The study randomly assigned 131 patients to receive standard chemotherapy and 126 to receive chemotherapy plus goserelin by injection once every four weeks.

Nearly half (45 percent) of the women on standard chemo stopped menstruating after two years.

Only 20 percent of the women receiving goserelin had stopped menstruating.

Pregnancies were twice as common in the goserelin group -- 21 percent compared to 11 percent.

And 89 percent of the women taking goserelin had no signs or symptoms of cancer four years later, compared to 78 percent of those receiving standard chemotherapy.

Survival was higher too -- 92 percent in the goserelin group and 82 percent in the standard chemo group.

Albain said women who need to undergo chemo for early breast cancer should consider taking goserelin to prevent premature ovarian failure.

Goserelin, known by the brand name Zoladex, was approved by the Food and Drug Administration for prostate cancer, certain benign gynecological disorders and certain breast cancers.

Source: AFP
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Sensory Processing Disorder (SPD)
First Dose of COVID-19 Vaccines May Improve Mental Health
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Ovulation Women and Cancer Breast Biopsy Pagets disease of the breast Mastitis Cancer and Homeopathy Breast Cancer Facts Cancer Facts Cancer Tattoos A Body Art 

Recommended Reading
Breast Cancer Screening using Mammogram
Breast cancer if detected early can be completely cured. Mammography is used to screen women for ......
Breast Cancer - Prevention and Management with Lifestyle Changes
Lifestyle choices may or may not cause breast cancer but healthy lifestyle changes can open up ......
Breast Cancer Management: Advances
The crab that invades the breast is no more a fear factor with all the advancements that medical ......
Breast Cancer during Pregnancy
Management of breast cancer during pregnancy or pregnancy associated breast cancer requires special ...
Breast Biopsy
Breast biopsy involves removing a sample of breast tissue to determine whether it is cancerous or .....
Mastitis
Mastitis is a common cause of tenderness, swelling and pain in breast, owing to inflammation in the ...
Ovulation
Ovulation is the time when an egg or ovum is released by female ovary, usually midway during the men...
Pagets disease of the breast
A detailed description of the Paget's disease of the breast, characteristic signs and symptoms, dete...
Tattoos A Body Art
Tattoos are a rage among college students who sport it for the ‘cool dude’ or ‘cool babe’ look...
Women and Cancer
Cancer is one of the frequently talked about and most feared disease that falls under the genre of l...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use