About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Five Genetic Variants Influencing the Size of Human Brain Discovered

by Vishnuprasad on January 27, 2015 at 4:28 PM
Font : A-A+

Five Genetic Variants Influencing the Size of Human Brain Discovered

A team of international researchers has discovered five genetic variants that influence the size of structures within the human brain.

The findings were published this week in the journal Nature.

Advertisement

The study was led by Drs. Sarah Medland, Margie Wright, Nick Martin and Paul Thompson of the QIMR Berghofer Medical Research Institute in Australia. In the study, nearly 300 researchers analyzed genetic data and magnetic resonance imaging (MRI) scans from 30,717 individuals from around the world.

They examined genetic data from seven subcortical brain regions - nucleus accumbens, caudate, putamen, pallidum, amygdala, hippocampus and thalamus - and intracranial volume from MRI scans.
Advertisement

The goal was to determine how common genetic variants affect the structure of these seven subcortical brain regions, which are associated with memory, movement, learning and motivation, said Dr. Jessica Turner, associate professor of psychology and neuroscience at Georgia State, who organized some of the teams collecting and evaluating data from participants with schizophrenia.

Changes in these brain areas can lead to abnormal behavior and predisposition to disease.

Previous research has shown the brain's structure is shaped by genetic influences. According to the researchers, identifying genetic variants could provide insight into the causes for variation in human brain development and help to determine how dysfunction in the brain occurs.

"The team looked at several million base pairs or locations on the human genome. Through a large-scale, international data sharing and data-analysis-sharing effort, we were able to actually successfully identify genetic effects on the hippocampus, putamen and other brain regions that no one had ever successfully identified genetics effects on before," Turner said.



Source: Medindia
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Ways to Manage Stress during COVID-19 Pandemic
Can Adjusting Fatty Acid Intake Improve Mood in Bipolar Disorder Patients?
Insulin Resistance Doubles the Risk of Major Depressive Disorder
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Parkinsons Disease Parkinsons Disease Surgical Treatment Genetics and Stem Cells Brain Brain Facts Ataxia Christianson Syndrome Language Areas in The Brain Ways to Improve your Intelligence Quotient (IQ) How Do Viruses Mutate and Why Does it Matter? 

Recommended Reading
Brain Food
It is a myth that the brain quits generating new cells once you reach adulthood. They are ......
Brain Tumor
Brain tumors are the abnormal growth of brain cells that may be benign or metastatic. Brain tumors ....
Brain Exercises to Improve Memory
An active brain can certainly help in improving memory by strengthening the connections between ......
Electroencephalogram
An electroencephalogram (EEG) detects electrical activity in the brain using electrodes attached to ...
Ataxia
Ataxia affects coordination. Gait becomes unstable and the patient loses balance. The cerebellum or ...
Christianson Syndrome
Christianson syndrome is a condition that occurs due to mutations (abnormal changes) in the gene SLC...
How Do Viruses Mutate and Why Does it Matter?
Mutations are the sudden changes that occur in genetic materials. They occur as a part of evolution ...
Language Areas in The Brain
The mechanism of how human brain processes the language to express and comprehend the verbal, writte...
Parkinsons Disease
Parkinsonís disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...
Ways to Improve your Intelligence Quotient (IQ)
Intelligence quotient (IQ) is a psychological measure of human intelligence. Regular physical and me...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use