Vulvovaginal problems such as dryness and pain during intercourse may get reduced by estradiol tablets, finds a new study. The findings of this study are published in the journal of The North American Menopause Society (NAMS).
Moderate to severe vulvovaginal symptoms in postmenopausal women is associated with significant decreases in sexual functioning and quality of life. Although there are a number of treatment options available, not all of them have been put to the test and have been documented to work. In the article "Effects of vaginal estradiol tablets and moisturizer on menopause-specific quality of life and mood in healthy postmenopausal women with vaginal symptoms: a randomized clinical trial," results of a double-blind, placebo-controlled study compared the effectiveness of vaginal estradiol tablets and vaginal moisturizers.
With more than 300 postmenopausal women participating in the study, it was shown that low-dose vaginal estradiol tablets greatly improved quality-of-life scores compared with dual placebo. Treatment with vaginal moisturizers, in contrast, did not yield any more improvement than placebo. This is the first known study to associate method effectiveness with an improvement in the quality of life and mood.