Depression Increases the Risk of Back Pain

by Shirley Johanna on February 27, 2015 at 6:51 PM

 Depression Increases the Risk of Back Pain
People with symptoms of depression are likely to have back pain, reveals a new study. The results showed a significant association between symptoms of depression and low back pain.

On initial analysis considering the participants as individuals, rather than twins and therefore not accounting for genetic and familial factors, the odds of having back pain were about 1.6 higher for those with symptoms of depression and anxiety.

On analysis of twin pairs, which controls for genetic and familial factors that could influence the relationship between depression and back pain, the relationship remained significant, with a 1.7 increase in odds. The association was even stronger, more than a 2.3 increase in odds of low back pain associated with depression and anxiety, on analysis of dizygotic (non-identical) twins, who share half their genes.

On further analysis of monozygotic twins, who are genetically identical-the association between symptoms of depression and low back pain disappeared. This suggested that the strong association found in non-identical twins resulted from the "confounding" effects of common genetic factors influencing both conditions. For example, genes affecting levels of neurotransmitters such as serotonin and norepinephrine might affect the risk of both conditions.

Previous studies have shown a "consistent relationship" between back pain and depression, a combination that might complicate diagnosis and treatment. However, the nature of the association remains unclear. The new study was the first to examine the relationship between depression and low back pain using twin data to control for genetic and familial factors.

The finding that the association disappears after fully adjusting for genetics and familial confounders in identical twins suggests that "genetics was the main confounder" of the relationship between depression and back pain. Thus the commonly found association between these health conditions was probably not a true relationship, as there are other factors influencing it.

The study is published in the journal PAIN(r), the official publication of the International Association for the Study of Pain.

Source: Medindia

News A-Z
News Category
What's New on Medindia
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
Stroop Effect
Plant-Based Diet may Reduce the Risk of COVID-19
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Adolescence Depression Depression Stress Relief Through Alternative Medicine Andropause / Male Menopause Pregnancy and Complications Bereavement Holistic Management for Depression Tourette Syndrome Dealing with Menopause symptoms through lifestyle changes Tired All The Time 

Recommended Reading
Back Pain
Back pain or Backache is common due to poor posture, postural deformities and life style. Back pain ...
Reducing the High Burden of Chronic Low Back Pain
Standardized research methods are required to make greater progress toward reducing the high burden ...
Clinical Depression
Clinical Depression is a serious medical condition that affects majority of people at some point in ...
Depression Symptom Evaluation
Depression occurs due to alterations in the levels of neurotransmitters in the brain. ...
Andropause / Male Menopause
Andropause or male menopause causing low libido in a man is due to decreasing level of male hormones...
Bereavement refers to grief, pain and sadness following the loss of a loved one, especially during t...
Dealing with Menopause symptoms through lifestyle changes
You can deal with menopause symptoms such as hot flashes, weight gain and forgetfulness by making si...
Depression is one of the most common mental disorders affecting approximately 340 million people in ...
Holistic Management for Depression
Depression is a common disorder and many worldwide suffer from depression. Early recognition of symp...
Pregnancy and Complications
In-depth guide for expecting mothers to overcome health complications related to early or late pregn...
Tired All The Time
Tired All The Time (TATT) syndrome is not only about feeling of tired, however there are a host of o...
Tourette Syndrome
Tourette syndrome (TS) is a neurological disorder wherein the affected person makes repetitive and s...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use