About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Creation Of Blood Vessels From Stem Cells Found In Fat

by Rukmani Krishna on July 28, 2012 at 9:11 PM
Font : A-A+

 Creation Of Blood Vessels From Stem Cells Found In Fat

A new study has show than adult stem cells extracted during liposuction can be used to grow healthy new small-diameter blood vessels. These blood vessels can be used in heart bypass surgery and other procedures.

Millions of cardiovascular disease patients are in need of small-diameter vessel grafts for procedures requiring blood to be routed around blocked arteries.

Advertisement

These liposuction-derived vessels, grown in a lab, could help solve major problems associated with grafting blood vessels from elsewhere in the body or from using artificial blood vessels that are not living tissue, said Matthias Nollert, Ph.D., the lead author of the study and associate professor at the University of Oklahoma School of Chemical, Biological and Materials Engineering, in Norman, Okla.

"Current small-diameter vessel grafts carry an inherent risk of clotting, being rejected or otherwise failing to function normally," Nollert said.
Advertisement

"Our engineered blood vessels have good mechanical properties and we believe they will contract normally when exposed to hormones. They also appear to prevent the accumulation of blood platelets - a component in blood that causes arteries to narrow," Nollert added.

In the study, adult stem cells derived from fat are turned into smooth muscle cells in the laboratory, and then "seeded" onto a very thin collagen membrane.

As the stem cells multiplied, the researchers rolled them into tubes matching the diameter of small blood vessels. In three to four weeks, they grew into usable blood vessels.

Creating blood vessels with this technique has the potential for "off-the-shelf" replacement vessels that can be used in graft procedures, Nollert said.

The researchers hope to have a working prototype to test in animals within six months.

The new research was presented at the American Heart Association's Basic Cardiovascular Sciences 2012 Scientific Sessions.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Organ Donation Week 2022 - 'Take the Pledge to Save Lives'
Test your Knowledge on Heart Transplantation
Test Your Knowledge on Lung Transplantation
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Stem Cells - Cord Blood Thalassemia Stem Cells - Fundamentals Parkinsons Disease Surgical Treatment Genetics and Stem Cells Diet Lifestyle and Heart Disease Cholesterol - The Enigma Chemical Liposuction Quiz on Weight Loss Bone Marrow Transplantation 

Most Popular on Medindia

Color Blindness Calculator Find a Hospital Find a Doctor Turmeric Powder - Health Benefits, Uses & Side Effects Diaphragmatic Hernia Blood Pressure Calculator Post-Nasal Drip A-Z Drug Brands in India Loram (2 mg) (Lorazepam) Selfie Addiction Calculator
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use