Study author Don Gilden said, "Our analysis, which is the largest to-date, provides compelling evidence that the virus also reactivates in people over 60 in another way, triggering giant cell arteritis. It is the most common type of inflammation of blood vessels in the elderly, affecting an estimated 29 out of 100,000 people. Symptoms include a new severe headache, scalp tenderness, jaw discomfort, blurred vision, fever, weight loss and tiredness. Importantly, the cause of this condition has been uncertain, prompting the present study."
Researchers examined for evidence of the virus in 13 temporal artery biopsies of people who died and had no previous symptoms of giant cell arteritis and in 84 temporal artery biopsies of people with giant cell arteritis. All the biopsies were from people over the age of 50-years. They found the virus in 74 percent of the biopsies with giant cell arteritis and in only 8 percent of the normal skin biopsies.
The study appears online in the medical journal of the American Academy of Neurology.