About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Cancer Risk Increased by Higher Than Normal Levels of Vitamin B12

by Kathy Jones on November 19, 2013 at 6:38 PM
Font : A-A+

 Cancer Risk Increased by Higher Than Normal Levels of Vitamin B12

A study published November 18 in the Journal of the National Cancer Institute says that vitamin B12 is essential for maintaining healthy bodily function but higher than normal levels may indicate that a patient is at risk of developing certain cancers.

Previous studies had suggested an association between high Cbl levels and specific cancers.

Advertisement

To assess the association between high Cbl levels and risk of cancer of any type, Johan Arendt, BSc, of the Department of Clinical Epidemiology and the Department of Clinical Biochemistry of Aarhus University Hospital in Denmark, and colleagues used Danish Medical registries to review the records of 333,667 patients without cancer who had been referred for Cbl testing and to estimate the incidence of cancer in this population from 1998 to 2010.

The researchers excluded patients who had a cancer diagnosis before the date of plasma measurement and those who were receiving Cbl therapy. They found that the risk of cancer overall increased with higher Cbl levels, especially during the first year after measurement and for those with levels > 800pmol/L. They also found that after five years of follow-up, the risk for hematological and alcohol and smoking-related cancers remained high for those with levels > 800pmol/L.
Advertisement

The authors conclude that "...high plasma Cbl levels increased the risk of subsequently diagnosed cancer, mostly within the first year of follow-up." However, Arendt et al. note that high plasma Cbl levels are probably not related to normal Vitamin B12 intake because consumption of Cbl containing foods or supplements do not increase plasma Cbl levels substantially. Rather, high Cbl levels may result from some unknown malignant process.



Source: Eurekalert
Advertisement

Advertisement
Advertisement

Recommended Reading

Latest Cancer News

 Myelofibrosis: New Drugs to Revolutionize Treatment
The approvals of pipeline drugs such as momelotinib and Vonjo for myelofibrosis (a rare type of blood cancer) over some time will handle the critical unmet needs.
 Blood Vessels Can Kill Cancer Cells and Stop Breast Cancer Spread
New study highlights the dual role that blood vessels can play in cancer immunotherapy and eliciting anti-tumor immune responses or even preventing breast cancer spread.
 Weed Killer Agent Orange May Increase the Risk of Blood Cancer Among Veterans
New study evaluated the association between exposure to the chemical agent orange and the development of blood cancer with increased bleeding and blood clot formation.
Two Years: Optimal Duration of Immunotherapy in Advanced Lung Cancer
Study suggests two-year immunotherapy treatment for advanced lung cancer may be reasonable
Hope for Lethal Brain Tumors: Targeted Therapy Delays Glioma Progression
A ray of hope for glioma patients as targeted therapy boosts treatment duration.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Cancer Risk Increased by Higher Than Normal Levels of Vitamin B12 Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests