About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Asthma is a Leading Cause of Hospitalization in Preschoolers

by Bidita Debnath on December 19, 2017 at 11:43 PM
Font : A-A+

Asthma is a Leading Cause of Hospitalization in Preschoolers

Asthma is a chronic condition that causes inflammation and narrowing of the bronchial tubes, the passageways that allow air to enter and leave the lungs. Asthma affects almost 1 in 10 children in the U.S. and is a leading cause of emergency room visits and hospitalizations in preschoolers.

According to new research from Duke Health and collaborators, symptoms may be worse for children ages 2 to 5 who are overweight.

Advertisement


In a study publishing in the Journal of Clinical Immunology, preschoolers with a body mass index (BMI) beyond the 84th percentile who weren't using an inhaler had 70 percent more days with asthma symptoms per year than untreated peers of a healthy weight.

Compared to healthy-weight peers, asthma sufferers who were untreated and overweight suffered 37 more symptom-days -- more than five extra weeks -- per year. Researchers also found untreated children who were overweight had more asthma attacks than untreated peers of a healthy weight.
Advertisement

There is good news: obesity doesn't seem to lessen the effectiveness of corticosteroid inhalers, the standard treatment to ease asthma symptoms such as shortness of breath, coughing and chest pain, said Jason Lang, M.D., a pediatric lung specialist and director of the Duke Children's Pulmonary Function Laboratory, who led the study.

When used daily, inhalers reduced the number of symptom-days and asthma attacks in both healthy and overweight children, and may even be more protective to overweight children, the authors found.

"The impact of overweight and obesity on asthma has not been studied in the youngest asthma patients, and this finding is the opposite of what has been seen in older kids and adults who are overweight," Lang said. "Reports in older children and adults with asthma who are overweight have shown a poor response to inhaled corticosteroids to manage their asthma. This study suggests either pathways of inflammation are a bit different in preschool-aged patients, or that it takes years for obesity to reduce the effectiveness of steroid inhalers."

The study analyzed data from three randomized, controlled clinical trials conducted between 2001 and 2015 called INFANT, PEAK and MIST that included 736 children. One-third of participants had a BMI above the 84th percentile.

Some trial participants were randomly assigned to use inhalers daily while some used them intermittently; some received placebos and some received no treatment.

The authors believe this is the first study on whether obesity impacts asthma severity and the effectiveness of inhalers in preschoolers, but the study does have limitations, including that it was a retrospective analysis, one that searches back in time to seek patterns.

Prospective, or forward-looking, research with a larger number of children could offer more insights into the best asthma treatments for overweight preschoolers and include strategies that address weight loss, the authors said.

"This study uses the best, mostly highly controlled data to demonstrate that early-life weight gain does worsen the severity of asthma in the youngest patients," Lang said. "Weight does not hamper the effectiveness of inhaled steroids in preschoolers, but this study provides clear evidence that maintaining a healthy weight in preschoolers may be an effective strategy for controlling asthma."

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Health Benefits of Giloy
Breast Cancer Awareness Month 2021 - It's time to RISE
First-Ever Successful Pig-To-Human Kidney Transplantation
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Childhood Asthma Asthma Cholamandalam Health Insurance Policies Amyotrophic Lateral Sclerosis (ALS) Remedies for Seasonal Allergy Relief Allergy - Symptom Evaluation Wheezing Churg-Strauss Syndrome Tests for Asthma Stay Well This Winter 

Recommended Reading
Exposure to Particulate Matter Increases Risk of Asthma in Children
Exposure to coarse particulate matter (PM10-2.5) puts children at greater risk for asthma....
Helminths Increase Risk of Allergy, Asthma in Humans
The intestinal worms that are usually found in animals but if found in humans, it increases the ......
Digital Self-Guided Breathing Intervention for Asthma
A digital self-guided breathing retraining intervention that offers breathing exercises for asthma ....
Intake of Sugary Drinks During Pregnancy Linked to Childhood Asthma
Avoiding high intake of sugary beverages during pregnancy and in early childhood could be one of ......
Allergy - Symptom Evaluation
An allergic reaction may be mild or severe. It usually involves the skin, respiratory system, eyes,...
Amyotrophic Lateral Sclerosis (ALS)
Find out more about the degenerative disease- Amyotrophic lateral sclerosis....
Asthma
It's a lung condition characterized by inflammation of the bronchi and constriction of the airways t...
Childhood Asthma
Childhood asthma is a condition that affects airways in children and interferes with their daily act...
Cholamandalam Health Insurance Policies
Cholamandalam MS General Insurance Company (Chola MS) a joint venture of Murugappa Group & Mitsui Su...
Churg-Strauss Syndrome
Churg-Strauss Syndrome is a rare disease characterized by inflammation of blood vessels that can res...
Remedies for Seasonal Allergy Relief
Understanding the cause and mechanism of seasonal allergy can help in choosing the right treatment. ...
Stay Well This Winter
Winter is associated with staying huddled indoors, people scurrying home to escape the piercing wint...
Tests for Asthma
Do you find it difficult to breathe especially during the cold weather? You may need to get tested f...
Wheezing
Wheezing is a sound arising from the airways due to an obstruction or narrowing, which prevents the ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use