About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Antiretroviral Drug Exposure During Pregnancy Poses Risk of Developmental Problems in Infants

by Reshma Anand on February 23, 2016 at 5:28 PM
Font : A-A+

Antiretroviral Drug Exposure During Pregnancy Poses Risk of Developmental Problems in Infants

HIV-positive pregnant women who take anti-retroviral treatments (ARV) containing atazanavir may have children with developmental problems, said a new study.

The Pediatric HIV/AIDS Cohort study published in the Journal AIDS was conducted among 1000 infants whose mothers took HIV treatments during pregnancy. Researchers analyzed children belonging to two groups namely, whose mothers received ARV with atazanavir drug and without atazanavir drug during pregnancy.

Advertisement


Children were assessed for infant development using the Bayley Scales of Infant and Toddler Development-Third Edition, or "Bayley III." The results showed lower language development scores for infants whose mothers received atazanavir during the first, second and third trimester of pregnancy.

The social-emotional development was also less for these infants, but there was much difference only in children of mothers who initiated the treatment during the second or third trimester—but not the first trimester.
Advertisement

"Language score was about three points lower in the atazanavir group, compared to an average subscale score of 93; while social-emotional score was five points lower, compared to an average of 100. These differences may not have large clinical implications, but they add another risk to the constellation of existing biological and socio-environmental risk factors to which these children are often exposed," according to Dr.Caniglia and coauthors.

Reference: Caniglia, Ellen, et al. Atazanavir exposure in utero and neurodevelopment in infants: A comparative safety study, AIDS 2016, doi: 10.1097/QAD.0000000000001052.

Source: Medindia
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Test  Your Knowledge on Heart
Test Your Knowlege on Genes
Obesity in Teens Make Inroads into Early Atrial Fibrillation
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drug Toxicity Trimester of pregnancy Pregnancy and Exercise Home Pregnancy Test Pregnancy Psychological Changes In Pregnancy Drugs in Pregnancy and Lactation Breech Presentation and Delivery Air travel: To fly or not to fly Signature Drug Toxicity 

Most Popular on Medindia

Blood Donation - Recipients Daily Calorie Requirements Hearing Loss Calculator The Essence of Yoga Indian Medical Journals Loram (2 mg) (Lorazepam) Drug Side Effects Calculator How to Reduce School Bag Weight - Simple Tips Nutam (400mg) (Piracetam) Post-Nasal Drip
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Antiretroviral Drug Exposure During Pregnancy Poses Risk of Developmental Problems in Infants Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests