About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Aging of Brain is Conclusively Influenced by Genes

by Bidita Debnath on November 5, 2013 at 11:38 PM
Font : A-A+

 Aging of Brain is Conclusively Influenced by Genes

For the first time, researchers from the Texas Biomedical Research Institute in San Antonio and Yale University say that the decline in brain function in normal aging is conclusively shown to be influenced by genes.

"Identification of genes associated with brain aging should improve our understanding of the biological processes that govern normal age-related decline," said John Blangero, Ph.D., a Texas Biomed geneticist and the senior author of the paper. The study, funded by the National Institutes of Health (NIH), is published in the November 4, 2013 issue of the Proceedings of the National Academy of Sciences.

Advertisement

David Glahn, Ph.D., an associate professor of psychiatry at the Yale University School of Medicine, is the first author on the paper. In large pedigrees including 1,129 people aged 18 to 83, the scientists documented profound aging effects from young adulthood to old age, on neurocognitive ability and brain white matter measures. White matter actively affects how the brain learns and functions.

Genetic material shared amongst biological relatives appears to predict the observed changes in brain function with age. Participants were enrolled in the Genetics of Brain Structure and Function Study and drawn from large Mexican Americans families in San Antonio. Brain imaging studies were conducted at the University of Texas Health Science Center at San Antonio Research Imaging Institute directed by Peter Fox, M.D. "The use of large human pedigrees provides a powerful resource for measuring how genetic factors change with age," Blangero said.
Advertisement

By applying a sophisticated analysis, the scientists demonstrated a heritable basis for neurocognitive deterioration with age that could be attributed to genetic factors. Similarly, decreasing white matter integrity with age was influenced by genes. The investigators further demonstrated that different sets of genes are responsible for these two biological aging processes. "A key advantage of this study is that we specifically focused on large extended families and so we were able to disentangle genetic from non-genetic influences on the aging process," said Glahn.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
First Dose of COVID-19 Vaccines May Improve Mental Health
Printed Temperature Sensors help with Continuous Temperature Monitoring
Health Benefits of Giloy
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Parkinsons Disease Parkinsons Disease Surgical Treatment Ageing and Sleep Brain Brain Facts Ataxia Weaver Syndrome Telomere Shortening And Ageing Language Areas in The Brain Ways to Improve your Intelligence Quotient (IQ) 

Recommended Reading
Low Doses of Electric Jolts to Brain can Reduce Migraine Pain
Receiving low doses of electricity to your brain could be an effective way of reducing migraine or ....
Exposure Therapy Remodels Brain Region Linked With Fear
A new study reveals that exposure therapy remodels an inhibitory junction in the amygdala, a brain ....
Baby Brains Respond to Other's Actions, A First Step In Learning By Imitation
For adults, imitation may be the sincerest form of flattery but for babies it's their foremost tool ...
Brain Connectivity Can Predict Epilepsy Surgery Outcomes: Research
A discovery from the researchers of Case Western Reserve and Cleveland Clinic could provide ......
Ageing and Sleep
Sleep is a barometer of good health in the elderly. Sleep problems in the elderly are controlled by ...
Ataxia
Ataxia affects coordination. Gait becomes unstable and the patient loses balance. The cerebellum or ...
Language Areas in The Brain
The mechanism of how human brain processes the language to express and comprehend the verbal, writte...
Parkinsons Disease
Parkinson’s disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...
Telomere Shortening And Ageing
Telomeres are cap- like structures at chromosome ends that play an important role in ageing and in t...
Ways to Improve your Intelligence Quotient (IQ)
Intelligence quotient (IQ) is a psychological measure of human intelligence. Regular physical and me...
Weaver Syndrome
Weaver syndrome is a genetic disorder in which children show accelerated bone growth, advanced bone ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use