About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Aggressive, Tailored Treatment Boosts Survival Rates in Kidney Cancer Patients

by VR Sreeraman on November 3, 2008 at 4:29 PM
Font : A-A+

 Aggressive, Tailored Treatment Boosts Survival Rates in Kidney Cancer Patients

Aggressive, personalized treatment increases kidney cancer patient survival, according to a landmark study by researchers at University of California, Los Angeles.

The study of nearly 1,500 patients treated for kidney cancer at UCLA in the last 15 years shows that an aggressive, tailored treatment approach results in better survival rates and uncovered subsets of kidney cancer that behave differently and need to be treated accordingly.

Advertisement

The one-size-fits-all approach traditionally used in kidney cancer treatment should be changed based on the results of the study, the longest to date to analyze kidney cancer patients and their outcomes, said Dr. Arie Belldegrun, senior author of the study, a professor of urology and a researcher at UCLA's Jonsson Comprehensive Cancer Center.

"This is the most important work that we've done out of the kidney cancer program at UCLA," Belldegrun said.

"We outline the foundation for personalized kidney cancer therapy. We have shown that not all kidney cancer patients are the same, not all localized kidney cancers are the same and not all metastatic kidney cancers are the same," the expert added.
Advertisement

The study has been published in the Nov. 1, 2008 issue of Cancer, the peer-reviewed journal of the American Cancer Society.

The study found that patients with localized kidney cancer, cancer that has not spread to other organs, could have either low, intermediate or high risk cancers based on the chance for recurrence. Patients with cancers that have already spread also fell into similarly different subsets. Some have better outcomes while others may have very aggressive cancers that may not warrant treatment.

"We showed for the first time, using an integrated staging system developed at UCLA, that we can identify which patients with localized disease fall into the low, intermediate and high risk subsets and which patients with metastasized cancers are either low, intermediate or high risk patients," Belldegrun said.

"Now we can make treatment decisions based on that," the expert added.

If a patient with localized cancer is identified as low risk, his five-year survival rate is expected to be 97 percent, while his 10-year survival rate is 92 percent. An intermediate risk patient with localized disease would have a five-year survival rate of 81 percent and a 10-year survival rate of 61 percent. A high risk patient has a five-year survival rate of 62 percent, with a 10-year survival of 41 percent.

"All of these patients with cancers that have not spread present to their doctors with presumably localized disease and in the past they may have been treated the same way. They need to be treated individually according to their risk levels," Belldegrun said.

The study showed that a patient with low-risk, localized kidney cancer could be treated only with surgery and expect an excellent outcome. Such a move would spare the patient from having to undergo radiation or immunotherapy, which result in harsh side effects. However, for a patient with high-risk, localized kidney cancer, surgery would not be enough.

Source: ANI
SRM/SK
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
First-Ever Successful Pig-To-Human Kidney Transplantation
World Osteoporosis Day 2021 -
Spirituality and Mental Health
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cancer and Homeopathy Urinary Stones In Children Vesico-Ureteric Reflux Causing UTI in Children Hydronephrosis / Antenatal Counseling Kidney Disease Cancer Facts Cancer Kidney Hematuria Kidney Health 

Recommended Reading
Anatomy of Urinary System - Animation
Animation & slides showing anatomy of urinary system and the role of kidneys in getting rid of the ...
Robotic Surgery for Kidney Cancer
A team of surgeons at NewYork-Presbyterian Hospital/Columbia University Medical Center are ......
Hematuria
Hematuria is a condition marked by the presence of red blood cells (erythrocytes) in the urine. The ...
Hydronephrosis / Antenatal Counseling
Currently most pregnant women undergo one or two ultrasound scans during their pregnancy....
Urinary Stones In Children
There is a wide misconception that only adults develop stones. On the contrary kidney stones are ver...
Vesico-Ureteric Reflux Causing UTI in Children
Bacterial infection of urinary bladder can cause pain and burning sensation while passing urine. Abn...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use